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How long does tadalafil last?

Photo of Generic 10mg tadalafil and branded 10mg Cialis medicine packs
Generic 10mg tadalafil and branded 10mg Cialis packs

Tadalafil is a drug used to treat erectile dysfunction. It is a type of PDE5 inhibitor. Tadalafil is a generic or drug name – ‘Cialis’ is a branded form of tadalafil.

One question men frequently ask when trying to choose a PDE5 inhibitor, is how long does it last?

Keeping it simple, tadalafil lasts for 36 hours and sometimes longer, and has the longest duration of action of all the PDE5 inhibitors. This compares for example to sildenafil (Viagra) which lasts for around 4 hours.

In addition, absorption of tadalafil is not affected by food, so it can be taken at any time before, during, or after a meal.


36 hours – really?

Yes, although this does not mean a continuous erection for 36 hours. Like all PDE5 inhibitors, tadalafil requires sexual stimulation to work – ie: you only get an erection when you want to.

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Once daily tadalafil

Once daily tadalafil 5mg
Tadalafil 2.5mg and 5mg can be used on a daily basis

Tadalafil is the medical – or generic – name for the Cialis brand of erectile dysfunction medicine. Tadalafil works in the same way as sildenafil (Viagra), however whereas sildenafil lasts for around 4 hours, tadalafil remains active for up to 36 hours, hence why it is sometime called the weekend pill. This does not mean you will have an erection for 36 hours, only when required, eg: when sexually aroused.

Most men take tadalafil as and when they need it 30 minutes or more before sexual activity. The usual starting dose is tadalafil 10mg, which – depending on effectiveness – may be increased to 20mg or decreased to 5mg.

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Is generic Cialis set to become the new Viagra?

Photo of generic Viagra and generic Cialis packs

Viagra became a powerhouse of a brand by promising to power up the sex life of couples across the globe. Viagra has become synonymous with helping men to get and keep an erection and has become a hot topic of conversation, there are even jokes about it:

What’s the difference between the first honeymoon and the second?
First honeymoon, Niagara. Second honeymoon, Viagra!

Let’s not for one moment, think of erectile dysfunction as a laughing matter. But, like all well-known brands, Viagra does draw attention. Read in full

What’s the difference between tadalafil and other ED treatments?

Happy couple after man takes tadalafilOne in ten men will experience sexual problems at some point. It’s fair to say that erectile dysfunction (ED) is a very real problem and can affect men across the spectrum. It doesn’t matter if you are gay, straight or bisexual – erectile dysfunction doesn’t discriminate. ED, or impotency, does tend to affect more mature males, but again, that’s not a given. A younger man going through a particularly stressful time or suffering from a medical problem may be just as likely to suffer from ED.

So, we are well aware of the problem but what can be done about erectile dysfunction? There are numerous treatments available. These include counselling or sex therapy, using medication (such as Viagra or Cialis), using equipment to assist (eg a vacuum pump), undergoing surgery, injections, implants and suppositories, or trying out alternative therapies. Read in full

Generic Cialis (tadalafil) prices

Generic Cialis tadalafil 20mgLilly’s patent for Cialis expired in the UK 14 November 2017, allowing other drug companies to sell generic Cialis marketed as ‘tadalafil’.

Cialis is the original brand name for tadalafil, the active ingredient in Cialis. Cialis (tadalafil) was the second erectile dysfunction drug developed, after Viagra (sildenafil).

Within days of the patent expiry several companies released generic tadalafil products at much lower cost than branded Cialis. Read in full

Side effects of Cialis

Photo of senior man reading Cialis advice leafletCialis is a treatment for erectile dysfunction. It works in a similar way to Viagra (sildenafil), Levitra, and Spedra, and has similar side effects.

The proper medical name for Cialis is tadalafil. Tadalafil, like the other commonly used erectile dysfunction tablets, is a PDE5 inhibitor, which means it works by inhibiting an enzyme called phosphodiesterase. This in turn changes the blood flow in the penis and improves erections.

A single Cialis tablet will usually remain active for 36 hours, which is longer than Viagra/sildenafil, Levitra, or Spedra. Cialis is sometimes called the ‘weekend pill’ because it works for longer than other treatments. Like other erectile dysfunction tablets, Cialis only works if there is sexual stimulation. If there is no stimulation, Cialis remains inactive. After 36 hours the effects wear-off.

The patent for Cialis expired November 2017 and lower cost generic Tadalafil is now available.

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Generic Cialis set to hit the market 14 November 2017

Generic tadalafil is now available in the UK

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Cialis pack with patent expired graphicThe so-called ‘weekend pill’ will soon be made by generic manufacturers, as Eli Lilly’s patent on the drug is expected to expire in the UK 14 November 2017, and will be made available soon after from Dr Fox.

The patent for Cialis expired in March 2015 in Brazil, and is now available in that country as generic tadalafil from Sandoz.

Cialis comes onto the scene

Containing the active ingredient tadalafil, Cialis was introduced to the market in 2003, to compete with Pfizer’s erectile dysfunction medicine Viagra. It was originally developed to relieve frequent urination or weak flow of urine in patients with enlarged prostates, but it also helps increase blood flow to the penis. Read in full