Differin

Differin cream and gel topical, containing retinoid (adapalene 0.1%) applied once daily to treat acne as part of a treatment plan.

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5 stars Dr Fox rated 'Excellent'

How to buy online

  1. Read medical information about acne treatment
  2. Answer medical questions to check for eligibility
  3. Reviewed by doctors - posted from UK pharmacy

Prices

Acne treatmentQuantityCost
Differin cream (adapalene 0.1%)45 grams£22.00
Differin cream (adapalene 0.1%)90 grams (2 x 45 grams)£39.00
Differin gel (adapalene 0.1%)45 grams£22.00
Differin gel (adapalene 0.1%)90 grams (2 x 45 grams)£39.00

Dr Fox charges a small prescription fee per order.

Prescription fees

Dr Fox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.

Prescriptions are issued by our doctors online and sent electronically to our pharmacy.

If you have your own private paper prescription please post to our pharmacy (details).

Dr Fox prices are 25%–50% lower than other UK online clinics.

Order valuePrescription fee
up to £10£1.00
up to £20£2.00
up to £40£3.00
over £40£4.00

Delivery charges

UK delivery only: £2.90 per consultation via Royal Mail 24 Signed For (1-3 working days with tracking).

Parcel forwarding services are not permitted. Use only UK home or work delivery address.

Returns and refunds - unwanted items can be returned within 14 working days for a full refund.

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About Differin

Galderma

Differin is a once daily topical treatment for acne. The active ingredient, adapalene, reduces spots and inflammation. Adapalene is a type of medicine known as a retinoid and is supplied in the UK by the pharmaceutical company Galderma.

Differin should be applied to acne prone areas, usually in the evenings, to areas of the face, back and chest affected by spots and inflammation, particularly where blackheads and whiteheads are present.

Whats a good treatment plan?

Treatment with Differin should be continued for at least 8 weeks. If after that time there is no improvement, treatment should be stopped or new types of treatment should be added.

After 3 months, treatment should be reviewed, and if acne has cleared Differin can be stopped. Acne may not come back, and if it does treatment can be restarted. Both Differin and over the counter benzoyl peroxide can be used long term (for many months or years) if needed.

With other acne treatments

Differin can be used with topical preparations containing clindamycin (Duac) or erythromycin (Zineryt) or benzoyl peroxide (non-prescription medicine). When other topical medicines are used with Differin these are usually applied at different times of the day.

Differin should not be used at the same time with other topical retinoids.

Side effects of Differin – cautions

Localised side effects, notably soreness, redness and inflammation of the skin are common, particularly early in treatment. Treatment frequency should be reduced if this occurs, or stopped if there is marked inflammation.

Generalised side effects are unlikely, as little of the active ingredients are absorbed through the skin.

Using Differin more frequently than daily will not increase effectiveness, but will increase the chances of side effects.

Sensitivity to UV light is increased and sun avoidance measures, including the use of sunscreens, are recommended.

Differin is for topical use only. Avoid contact with mouth and eyes. If accidentally ingested contact a doctor straight away.

Pregnancy and breastfeeding

Avoid use in pregnancy. Differin can be used by breastfeeding women, although application to the chest area should be avoided.

Patient information leaflets

The 'Patient Information Leaflet' supplied with treatment must be read before use.

Differin Gel Patient Information Leaflet
Differin Cream Patient Information Leaflet

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Authored 19 November 2015
by Dr Tony Steele, MB ChB

Reviewed 15 January 2018 by Dr B. Babor, Dr A. Wood, Dr P. Hunt

Last updated 20 September 2018

Product reviews

Differin rated 5/5 in 6 product reviews

See over 16,900 service reviews of Dr Fox

Differin Gel

The best i love this product

28/06/2018 02:33
Anonymous Verified

Differin Gel

Perfect if you’re struggling with persistent acne on face & body!

28/05/2018 18:11
Anonymous Verified

Differin Cream

Works well after a period of time although over applying does cause very dry itchy skin

17/01/2018 19:03
M. Wilcox Verified

Differin Gel

The only thing that has ever worked for my acne skin.

01/11/2017 02:26
Anonymous Verified

Differin Cream

Persevere with treatment as you'll notice a big improvement after 6-8 weeks!

21/12/2016 09:39
I. Galea Verified

More Differin reviews

The order process

Answer short medical questionnaire

Choose treatment, register, and pay

Doctor issues prescription online

Medicine posted direct from pharmacy