Lariam (mefloquine 250mg) anti-malaria tablets - caution advised.

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How to buy online

  1. Read medical information about malaria tablets
  2. Answer medical questions to check for eligibility
  3. Reviewed by doctors - posted from UK pharmacy


Lariam may cause serious mental issues in some people. Please see warnings and cautions information below.


Malaria prophylaxisQuantity (trip length)Cost
Mefloquine 250mg (Lariam)8 tablets (1 week trip)£22.90
Mefloquine 250mg (Lariam)9 tablets (2 week trip)£24.10
Mefloquine 250mg (Lariam)10 tablets (3 week trip)£25.90
Mefloquine 250mg (Lariam)11 tablets (4 week trip)£28.10
Mefloquine 250mg (Lariam)12 tablets (5 week trip)£30.10
Mefloquine 250mg (Lariam)13 tablets (6 week trip)£32.10
Mefloquine 250mg (Lariam)15 tablets (8 week trip)£35.90
Mefloquine 250mg (Lariam)19 tablets (12 week trip)£48.10
Mefloquine 250mg (Lariam)32 tablets (24 week trip)£79.00
Mefloquine 250mg (Lariam)58 tablets (52 week trip)£135.00

Prescription issued online - small prescription fee per order.

Prescription fees

Dr Fox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.

Prescriptions are issued by our doctors online and sent electronically to our pharmacy.

If you have your own private paper prescription please post to our pharmacy (details).

Dr Fox prices are 25%–50% lower than other UK online clinics.

Order valuePrescription fee
up to £10£1.00
up to £20£3.00
up to £50£5.00
up to £100£8.00
over £100£10.00

Delivery charges

UK delivery only: £2.90 per consultation via Royal Mail 24 Signed For (1-3 working days with tracking).

Parcel forwarding services are not permitted. Use only UK home or work delivery address.

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About Lariam

Lariam 250mg tablets (mefloquine)

Lariam (manufactured by Roche) is a medicine which is taken once weekly to reduce the chances of catching malaria. Each tablet contains 250mg of the active ingredient mefloquine.

Uses of Lariam

Malaria is caused by a parasite which is passed from one person to another by mosquito bites. No one medicine is effective against all types of malaria. Recommendations for malaria prevention in different parts of the world can be found at the NHS Scotland Fit for Travel website. Lariam is particularly useful in areas where malaria is difficult to treat. No malaria prevention tablet is 100% effective.

Lariam is a prescription medicine. It is available in the UK only on prescription or through specialist travel clinics or specialist pharmacies. Unregulated supplies may be fake and may be ineffective.

Taking Lariam tablets

Take one Lariam tablets on the same day each week, starting at least 10 days before entering malaria areas. Continue weekly tablets whilst in the malaria area and for four weeks after leaving. The minimum course of treatment is 6 weeks. Swallow tablets whole with plenty of water, preferably after a meal.


Checks for suitability are carried out online as part of Dr Fox consultations. Alternatives to Lariam tablets for malaria prevention are available through Dr Fox.

Lariam can be taken by most people, although it is not suitable for everyone, particularly people who are prone to depression, anxiety or psychiatric symptoms or illness. Travel is often stressful and Lariam may exacerbate stress related symptoms. Some people may experience agitation, nightmares, poor sleep and other psychiatric or psychological symptoms. These symptoms can sometimes be long lasting. If symptoms of this nature develop, Lariam should be stopped. More detail can be found in the patient information leaflet supplied with Lariam tablets.

Lariam should not be taken by people who are allergic to mefloquine or chloroquine, or by people who have mental health problems, a history of fits or seizures, or severe liver problems. The anaesthetic halofantrine should not be used for 15 weeks after the last dose of mefloquine.

Side effects of Lariam

Most people can take Lariam without significant side effects. However, Lariam may cause serious mental health problems in some people, and in rare cases can these can persist. Seek medical help immediately if any of the following occur: suicidal thoughts, self-harming behaviour, severe anxiety. Consult a doctor if the following occur: feelings of mistrust towards others (paranoia), seeing or hearing things that are not there (hallucinations), nightmares, depression, feeling restless, unusual behaviour or feeling confused. Other side effects are list in the patient information leaflet.

The most common side effects of Lariam, occurring in 1 in 10 people include, sleeping problems (sleepiness, unable to sleep, bad dreams). Less Common, affecting up to 1 in 10 people are, dizziness, headache, problems with vision, loss of balance (vertigo), feeling sick (nausea), being sick (vomiting), diarrhoea, stomach ache (abdominal pain) and itching.

Care should be taken whilst driving and operating machinery as Lariam may affect sensorimotor skills. Small numbers of people experience persistent disturbance of balance after taking Lariam, although this is rare. 

Other side effects are listed in the patient information leaflet of Lariam.

Lariam and other medicines

Some prescribed and non-prescribed medicines can interact with Lariam, notably some other malaria tablets, but also medicines used to treat some heart conditions and depression. People who take other medicines MUST check the patient information of Lariam before starting treatment.

Pregnancy and breastfeeding

Pregnant women are usually advised not to take Lariam, unless the benefits outweigh the risks of malaria. A specialist in travel medicine should be consulted. Women of childbearing age, who might otherwise become pregnant, should take effective contraception whilst taking Lariam and for 3 months after stopping it. Breastfeeding whilst taking Lariam is not recommended.

Lariam for children

Lariam can be used in children and babies. Dr Fox prescribes only for people 18 years and over. See more information about malaria tablets for children.

Preventing Malaria

In addition to taking a recommended malaria tablets, malaria risk can be reduced by avoiding mosquito bites. Avoid being outside at the times of day when mosquitos bite, usually the evenings, cover up with long sleeved shirts and trousers and use repellents and sleep under nets in screened rooms, where possible.

Patient information leaflet

The 'Patient Information Leaflet' supplied with Lariam must be read before taking tablets.

Lariam Patient Information Leaflet

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Authored 01 April 2016
by Dr Tony Steele

Reviewed 14 August 2017 by Dr B. Babor, Dr A. Wood, Dr P. Hunt

Last updated 3 March 2018

The order process

Answer short medical questionnaire

Choose treatment, register, and pay

Doctor issues prescription online

Medicine posted direct from pharmacy

Customer reviews

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