Duac gel (benzoyl peroxide 3% and clindamycin 1%) contains antibiotic and peeling agent used to treat acne as part of a treatment plan. Available to buy online from Dr Fox.

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Buy Duac online in UK

How to order Duac online for UK delivery:

  1. Read medical information about acne treatment
  2. Answer medical questions to check for eligibility
  3. Reviewed by doctors - posted from UK pharmacy


Acne treatmentQuantityCost
Duac Once Daily Gel (benzoyl peroxide 3% and clindamycin 1%)30gm tube£19.50
Duac Once Daily Gel (benzoyl peroxide 3% and clindamycin 1%)60gm tube£35.80

Price match guaranteePrice match guarantee
Prescription issued online - small prescription fee per order.

Delivery charges

UK delivery only: £2.90 per consultation via Royal Mail 24 Signed For (1-3 working days with tracking).

Parcel forwarding services are not permitted. Use only UK home or work delivery address.

Returns and refunds - unwanted items can be returned within 14 working days for a full refund.

Prescription fees

Dr Fox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.

Prescriptions are issued by our doctors online and sent electronically to our pharmacy.

Order valuePrescription fee
up to £10£1.00
up to £20£2.00
up to £40£3.00
over £40£4.00

If you have your own private paper prescription please post to our pharmacy (details).

Dr Fox prices are 25%–50% lower than other UK online clinics.

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About Duac

Duac Gel contains the antibiotic clindamycin and the peeling agent benzoyl peroxide. Both these ingredients reduce the bacteria associated with acne, and in addition benzoyl peroxide help to unblock pores and reduce whiteheads and blackheads. Duac is therefore likely to reduce spots, infection and inflammation.

Duac is a useful dual action second-line treatment for acne which is not responding to antibiotics or peeling agents on their own.

Duac is applied once daily. One finger tip amount of gel will cover the whole face.

Side effects of Duac

The commonest side effect is redness and soreness, particularly in the first few weeks of treatment. This is mainly due to the benzoyl peroxide component, which is a mild irritant. If inflammation is marked and persistent, Duac should be applied less frequently or even stopped. If there is a marked reaction, treatment should be stopped straight away.

Duac contains an antibiotic and therefore should not normally be used with other acne treatments containing antibiotics. A small amount of antibiotic is absorbed through the skin and has the potential to cause intestinal upset, although this is unlikely.

Duac makes the skin more than usually sensitive to sunlight. Sun screens, sun hats and sun avoidance are all advisable.


Pregnant and breastfeeding women should not use Duac, although there is no known identified incidence of significant adverse effects.

Excess gel can stain clothing and even bleach hair.

Duac is a topical preparation. It should not be ingested or be applied to the lips. Accidental ingestion should be reported to a doctor straight away.

How to use

As with all acne treatments, Duac may take some time to work. Some improvement should be seen after about 5 weeks. If after 8 weeks there is no improvement, treatment should be stopped.

The manufacturers recommend usage for up to 12 weeks. Once bacteria become resistant to the antibiotic component, clindamycin, the gel will become less effective.


Topical acne medicines containing tretinoin, isotretinoin or tazarotene may be made less effective by Duac and should not be used at the same time.

Topical preparations containing antibiotics, such as Dalacin T or Zineryt should not be used at the same time. Likewise creams, gels or lotions containing benzoyl peroxide should also not be used at the same time.

Patient Information Leaflet

Illustration of patient leaflet from medicine packet

The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine and must be read before taking the medicine. It is written for patients and gives information about taking or using a medicine.

Duac patient leaflet

Dr Barbara Babor

Authored 19 November 2015 by Dr B. Babor
MB ChB Dundee University 1996. NHS GP and dermatology specialist.

Reviewed by Dr Tony Steele, Dr A. Wood, Dr P. Hunt
Last reviewed 15 January 2018
Last updated 7 July 2021


Product reviews

Duac rated 4.68/5 in 25 product reviews

See over 30,000 service reviews of Dr Fox

Duac Gel

This cleared my acne very nicely

17/07/2021 18:51
A. Njie Verified

Duac Gel

This product is the best I've ever tryed!!!!

28/04/2021 20:14
Anonymous Verified

Duac Gel

Really good

21/03/2021 09:08
Anonymous Verified

Duac Gel

Couple of days use and it has completely cleared up my spots. Still have a couple under the skin but not red and visible like they were. I would recommend.

07/12/2020 14:07
Anonymous Verified

Duac Gel

good product

25/11/2020 12:59
Anonymous Verified

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The order process

Choose medication, register, and pay

Doctor issues prescription online

Pharmacy team post medication direct