Duac gel (benzoyl peroxide 3% and clindamycin 1%) contains antibiotic and peeling agent used to treat acne as part of a treatment plan. Applied once daily Duac reduces spots, infection and inflammation.

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How to buy online

  1. Read medical information about acne treatment
  2. Answer medical questions to check for eligibility
  3. Reviewed by doctors - posted from UK pharmacy


Acne treatmentQuantityCost
Duac Once Daily Gel (benzoyl peroxide 3% and clindamycin 1%)30gm tube£19.50
Duac Once Daily Gel (benzoyl peroxide 3% and clindamycin 1%)60gm tube£35.80

Prescription issued online - small prescription fee per order.

Delivery charges

UK delivery only: £2.90 per consultation via Royal Mail 24 Signed For (1-3 working days with tracking).

Parcel forwarding services are not permitted. Use only UK home or work delivery address.

Returns and refunds - unwanted items can be returned within 14 working days for a full refund.

Prescription fees

Dr Fox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.

Prescriptions are issued by our doctors online and sent electronically to our pharmacy.

If you have your own private paper prescription please post to our pharmacy (details).

Dr Fox prices are 25%–50% lower than other UK online clinics.

Order valuePrescription fee
up to £10£1.00
up to £20£2.00
up to £40£3.00
over £40£4.00
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About Duac

Duac Gel contains the antibiotic clindamycin and the peeling agent benzoyl peroxide. Both these ingredients reduce the bacteria associated with acne, and in addition benzoyl peroxide help to unblock pores and reduce whiteheads and blackheads. Duac is therefore likely to reduce spots, infection and inflammation.

Duac is a useful dual action second-line treatment for acne which is not responding to antibiotics or peeling agents on their own.

Duac is applied once daily. One finger tip amount of gel will cover the whole face.

Side effects of Duac

The commonest side effect is redness and soreness, particularly in the first few weeks of treatment. This is mainly due to the benzoyl peroxide component, which is a mild irritant. If inflammation is marked and persistent, Duac should be applied less frequently or even stopped. If there is a marked reaction, treatment should be stopped straight away.

Duac contains an antibiotic and therefore should not normally be used with other acne treatments containing antibiotics. A small amount of antibiotic is absorbed through the skin and has the potential to cause intestinal upset, although this is unlikely.

Duac makes the skin more than usually sensitive to sunlight. Sun screens, sun hats and sun avoidance are all advisable.


Pregnant and breastfeeding women should not use Duac, although there is no known identified incidence of significant adverse effects.

Excess gel can stain clothing and even bleach hair.

Duac is a topical preparation. It should not be ingested or be applied to the lips. Accidental ingestion should be reported to a doctor straight away.

How to use

As with all acne treatments, Duac may take some time to work. Some improvement should be seen after about 5 weeks. If after 8 weeks there is no improvement, treatment should be stopped.

The manufacturers recommend usage for up to 12 weeks. Once bacteria become resistant to the antibiotic component, clindamycin, the gel will become less effective.


Topical acne medicines containing tretinoin, isotretinoin or tazarotene may be made less effective by Duac and should not be used at the same time.

Topical preparations containing antibiotics, such as Dalacin T or Zineryt should not be used at the same time. Likewise creams, gels or lotions containing benzoyl peroxide should also not be used at the same time.

Patient information leaflet

The 'Patient Information Leaflet' supplied with medication must be read before use.

Duac Once Daily Gel Patient Leaflet

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Authored 19 November 2015
by Dr Tony Steele, MB ChB

Reviewed 15 January 2018 by Dr B. Babor, Dr A. Wood, Dr P. Hunt

Last updated 20 September 2018

Product reviews

Duac rated 4.56/5 in 9 product reviews

See over 16,900 service reviews of Dr Fox

Duac Gel

It improved my acne and reduced spots. Would recommend it to acne sufferers

15/11/2018 20:07
Anonymous Verified

Duac Gel

Best cream I ever used made a really big difference on my face.

02/07/2018 11:40
Anonymous Verified

Duac Gel

works much better than the other treatment my GP put me on

20/06/2018 08:29
Anonymous Verified

Duac Gel

really effective in clearing up my acne on my cheeks

08/01/2018 21:12
Anonymous Verified

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The order process

Answer short medical questionnaire

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