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How does Colpermin work?

Colpermin is a gelatin capsule which allows the peppermint oil to be released directly into the gut just before the large bowel. The oil then relaxes the large bowel muscles, the pressure in the bowel drops, and symptoms of pain and bloating are reduced.

Who can take Colpermin?

Colpermin is suitable for most people suffering from the spasms, cramps and bloating of IBS.

It also contains peanut (arachis) oil so it is not suitable for those who are allergic to peanuts or soya.

It is important to be sure that your symptoms are caused by IBS and not something more serious.

If any of the following apply, check with your GP before using Colpermin:

• Changed or new symptoms especially in women.
• Over 40 years old with first symptoms.
• New symptoms of blood in your stool or motions.
• Feeling nauseous.
• Losing weight without dieting.
• Lost your appetite.
• Pale and tired.
• Severely constipated.
• Running a high temperature (fever).
• Travelled abroad recently.
• Are or may be pregnant.
• Urinary symptoms as well.

Colpermin is licensed to treat adults and children from 15 years of age, however Dr Fox can supply treatment to adults only.

How to take Colpermin

• Take care not to damage the capsule when removing it from the blister pack.
• Colpermin capsules should be swallowed whole with water. Do not chew, as this damages the capsule.
• Do not take at the same time as food, or indigestion remedies.
• Take 1 or 2 capsules 3 times a day. Symptoms should settle completely within two to three weeks. Capsules can be taken for 2-3 months if required.

Taking Colpermin with other medication

There are no known interactions between other medications and Colpermin.

Pregnancy and breastfeeding

As with all medications, caution is advised when considering taking Colpermin if you are pregnant or breastfeeding. Discuss potential risks and benefits with your own GP before taking Colpermin if you are pregnant or breastfeeding.

Possible side effects

Side effects are unusual with Colpermin but may include:

• A burning feeling in the mouth.
• Irritation around the back passage (anus).
• Heartburn or acid reflux (if this occurs, stop taking Colpermin).
• Nausea or vomiting.

There are also very rare intolerance or allergic reactions which may be worsened by alcohol. Symptoms are rash, headache, slow pulse, shaking, loss of coordination. If affected, stop taking Colpermin and consult a doctor or telephone the 111 service. If symptoms are severe, get emergency medical help. Telephone 999 in the UK.

Further information can be found in the manufacturer's patient information leaflets.

Other measures to help symptoms of IBS

Diarrhoea and bloating - reduce insoluble fibre like bran, wholegrain bread, and brown rice. Reduce caffeine, alcohol, fizzy drinks, and gas-producing foods like beans and cabbage.

Constipation - try adding more soluble fibre like oats and linseed, or soluble fibre supplements like Fybogel (ispaghula). Increase the soluble fibre gradually or bloating and wind may get worse. It may take several weeks for optimal benefits.

Regular physical activity is also helpful for the bowels. Aim for 30 minutes of moderate activity at least 5 days per week.

It is also important to drink plenty of fluids (at least 8 cups per day) when constipated, especially if taking Fybogel.

Further information

• NHS - IBS - Diet, lifestyle and medicines
• NHS - Peppermint oil