Prevent and reduce jet lag symptoms with Melatonin 3mg tablets available to buy online from Dr Fox from 75p each.

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Buy Melatonin online in UK

How to order Melatonin online for UK delivery:

  1. Read medical information about Melatonin and jet lag
  2. Answer medical questions to check for eligibility
  3. Reviewed by doctors - posted from UK pharmacy (tracked 24hr service)


Prices of Melatonin 3mg tablets from Dr Fox Pharmacy (in stock)
30 tablets60 tablets
Melatonin 3mg£23.80£45.30

Prescription fees

Dr Fox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.

Prescriptions are issued by our doctors online and sent electronically to our pharmacy.

Order valuePrescription fee
up to £10£1.00
up to £20£2.00
up to £40£3.00
over £40£4.00

If you have your own private paper prescription please post to our pharmacy (details).

Dr Fox prices are 25%–50% lower than other UK online clinics.

Delivery charges

UK delivery only: £2.90 per consultation via Royal Mail 24 Signed For (1-3 working days with tracking).

Parcel forwarding services are not permitted. Use only UK home or work delivery address.

Returns and refunds - unwanted items can be returned within 14 working days for a full refund.

About Melatonin

Melatonin tablets contain the active medication melatonin. Melatonin 3mg tabs are used for the treatment of jet lag.

Jet lag, which often lasts a few days and can last up to a week or more, causes sleep disturbances, daytime tiredness, mild mental impairment, irritability, and reduced appetite. It is often unpleasant, and sometimes debilitating, affecting both business and holiday travel. Severity varies from person to person and on the number of time zones crossed, tending to be more severe in older people, and with flights from east to west.

You should get medical advice if you do not feel better or if you feel worse after 5 days.

What is Melatonin medication?

Melatonin is a naturally occurring hormone which helps regulate the body's day-and-night clock. The biological clock can be disturbed by travelling across time zones leading to jet lag. The severity of symptoms varies between individuals, but are generally worse and last longer the more time zones that are crossed. Melatonin tablets can help restore the normal day-and-night rhythm and reduce jet lag symptoms.

Can I get Melatonin on the NHS?

Melatonin medication for the treatment of jet lag is considered to be a 'travel medication', and like other travel medicines, is not available through the NHS. It is a prescription medicine which Dr Fox supplies through a private online prescription, posted from our UK pharmacy.

How many tablets do I need?

Treatment is taken for up to 5 days after arriving when one or two tablets are taken each evening. One pack of 30 tablets is enough for up three or six treatments depending on the number of tablets taken each day. Frequent travellers can take up to 16 courses of treatment in a year.

Can anyone take Melatonin?

Most people can take Melatonin, although people with some pre-existing medical conditions or those taking certain medicines should not take it. Further information is listed in the patient information leaflet supplied with the tablets. Melatonin is not suitable for under 18s.

How to reduce jet lag without medication

  • Before you travel try going to bed at a time closer to the destination bedtime.
  • Try to make sure you have enough sleep in the days before you travel.
  • Keep as calm and relaxed as possible during travel.
  • Drink plenty to keep hydrated.
  • Avoid more than a little alcohol.
  • Move around during the flight when you can.
  • Adjust the time on your watch to the destination time at the start of the journey.
  • Sleep during the journey if travelling West.
  • On arrival try to sleep and eat at destination times.
  • Try to avoid naps in the day.
  • Spend time out of doors where natural light helps with adjustment.


Talk to your doctor before taking Melatonin medication, if the following apply:

  • Epilepsy - frequency of fits may increase.
  • Autoimmune disease (where the body is 'attacked' by its own immune system).
  • Diabetes or impaired glucose tolerance, as this medicine may increase the level of glucose in your blood.
  • Impaired kidney function or liver function.
  • Smoking - may reduce the effect of Melatonin medication as smoking can increase the breakdown of melatonin by the liver.

Children and adolescents - not suitable for under 18 years, safety and efficacy are unknown.

Other medicines

Tell your doctor or pharmacist if you are taking or will take melatonin whilst also taking any of the following:

  • Fluvoxamine (used for the treatment of depression and obsessive-compulsive disorder), as fluvoxamine may increase the effect of melatonin.
  • Psoralens (used for the treatment of skin disorders e.g. psoriasis), as psoralens may increase the effect of melatonin.
  • Cimetidine (used for the treatment of stomach problems such as ulcers), as cimetidine may increase the effect of melatonin.
  • Estrogens (used in contraceptives or hormone replacement preparations), as estrogens may increase the effect of melatonin.
  • Quinolones (used in the treatment of bacterial infections), as quinolones may increase the effect of melatonin.
  • Rifampicin (used in the treatment of bacterial infections), as rifampicin may decrease the effect of melatonin.
  • Carbamazepine (used in the treatment of epilepsy), as carbamazepine may decrease the effect of melatonin.
  • Benzodiazepines and non-benzodiazepine hypnotics (medicines used to induce sleep, e.g. midazolam, temazepam, and zaleplon, zolpidem, zopiclone), as melatonin may enhance the sedative effect of such drugs, and may enhance certain side effects of zolpidem (morning sleepiness, nausea, confusion).
  • Warfarin (anticoagulants), as melatonin may influence the effect of the anticoagulant warfarin.

Melatonin tablets with alcohol and food drink

Alcohol should NOT be taken whilst taking melatonin. Alcohol can impair sleep and potentially worsen certain symptoms of jet lag (e.g. concentration, headache, morning fatigue).

Pregnancy, breastfeeding, and fertility

Seek medical advice, if you are pregnant or breastfeeding or think you may be pregnant or are planning to have a baby. Melatonin crosses into breast milk. The effects on babies is unknown and therefore it is not recommended. Melatonin crosses the placenta and the risks to the unborn are unknown. Women who might become pregnant MUST take contraception if taking melatonin.

Operating machinery and driving

Melatonin can decrease alertness for several hours after intake - do NOT drive or operate machinery after taking.

How to take

Adults only - 1 tablet daily for a maximum of 5 days. If not working, 2 tablets daily. Take first tablet(s) on arrival at destination at your usual bed-time. On the following days take at your usual bed-time - should not be taken before 20:00 hr or after 04:00 hr. Take tablets whole with water or other liquid (not alcohol), not within 2 hours before or after food.

Courses of melatonin treatment can be repeated for each episode of jet lag up to a maximum of 16 treatment periods per year.

If you have taken more than recommended, please contact your doctor, hospital, or pharmacy. Common symptoms of overdose are drowsiness, headache, dizziness, and nausea.

If you forget to take a tablet at bedtime and wake during the night you may take the forgotten dose but at no later than 04:00 hr. Do not take a double dose to make up for a missed dose.

If you stop taking Melatonin tablets, it will not have any withdrawal symptoms or harmful effects.

Side effects

Melatonin can cause side effects, although not everybody gets them.

Serious side effects

If you experience any of the following serious side effects stop taking and contact your doctor immediately.

Chest pain (uncommon affecting 1 in 100) and rare side effects (affecting up to 1 in 1,000 people) includes reduced red blood cells (anaemia), reduced white blood cells (increased risk of infection), reduced platelets (increased bruising or bleeding), disorientation, fainting, visual symptoms, feeling your heart (palpitations, pounding heart), and blood in the urine.

Allergic reactions, with swelling of the tongue and lining of the mouth can occur - frequency unknown.

Non-serious side effects

Common side effects (may affect up to 1 in 10 people), headache, drowsiness.

Uncommon side effects (may affect up to 1 in 100 people), irritability, nervousness, restlessness, abnormal dreams, anxiety, dizziness, high blood pressure, abdominal pain, upper abdominal pain, indigestion, mouth ulceration, dry mouth, nauseam Itching, rash, dry skin, excretion of glucose in the urine, excess protein in the urine, feeling unwell, Weight increase.

Rare side effects

(may affect up to 1 in 1000 people), high levels of certain fat molecules (triglycerides) in the blood, altered mood, aggression, increased sex drive, memory impairment, restless legs syndrome, ‘pins and needles’ sensation, watery eyes, hot flushes, vomiting, wind, excess saliva, bad breath, inflammation of the stomach lining, nail disorder, arthritis, muscle spasms, passing large volumes of urine, prolonged erection that might be painful, inflammation of the prostate gland, thirst, abnormal levels of electrolytes in the blood.

Frequency unknown; hypersensitivity reactions, high blood glucose level, flow of milk from the breasts (also in men).

Reporting of side effects

If you have any side effects, talk to your doctor or pharmacist, includes effects not listed above. You can also report side effects direct using the Yellow Card system -

Patient Information Leaflet

Illustration of patient leaflet from medicine packet

The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine and must be read before taking the medicine. It is written for patients and gives information about taking or using a medicine.

Melatonin 3mg Patient Leaflet

Dr Tony Steele

Authored 14 February 2020 by Dr Tony Steele
MB ChB Sheffield University 1983. Former hospital doctor and GP.

Reviewed by Dr B. Babor, Dr A. Wood, Dr P. Hunt
Last reviewed 17 February 2020
Last updated 18 October 2021


Product reviews

Melatonin rated 4.87/5 in 45 product reviews

See over 30,000 service reviews of Dr Fox


Amazing I can finally sleep better

07/10/2021 07:46
Anonymous Verified


Very very beneficial

03/07/2021 12:00
V. Budriene Verified


I find it very useful for inducing sleep

18/06/2021 12:24
Anonymous Verified


This really works for me. I get a tranquil night's sleep.

06/06/2021 12:48
Anonymous Verified


Worked really well, thank you.

25/05/2021 22:05
Anonymous Verified

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