Losec (omeprazole)

Omeprazole suppresses the symptoms of acid reflux for around 24 hours. Available to buy online from Dr Fox.

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5 stars Dr Fox rated 'Excellent'

How to buy online

  1. Read medical information about acid reflux treatment
  2. Answer medical questions to check for eligibility
  3. Reviewed by doctors - posted from UK pharmacy

Prices

Acid reflux/indigestion treatmentQuantityCost
Omeprazole 10mg (generic)28 capsules£7.95
Omeprazole 10mg (generic)56 capsules£11.95
Losec (Omeprazole) 10mg28 capsules£14.50
Losec (Omeprazole) 10mg56 capsules£23.10

Prescription issued online - small prescription fee per order.

Prescription fees

Dr Fox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.

Prescriptions are issued by our doctors online and sent electronically to our pharmacy.

If you have your own private paper prescription please post to our pharmacy (details).

Dr Fox prices are 25%–50% lower than other UK online clinics.

Order valuePrescription fee
up to £10£1.00
up to £20£2.00
up to £40£3.00
over £40£4.00

Delivery charges

UK delivery only: £2.90 per consultation via Royal Mail 24 Signed For (1-3 working days with tracking).

Parcel forwarding services are not permitted. Use only UK home or work delivery address.

Returns and refunds - unwanted items can be returned within 14 working days for a full refund.

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About Losec (omeprazole)

What is Losec (omeprazole)?

Losec is a brand name for a medicine called omeprazole, the active ingredient.

Omeprazole is a type of medicine called a proton pump inhibitor (PPI). PPIs have been in use for more than 25 years, and have been shown to be safe and effective treatments for acid reflux/heartburn, and a range of other gastric and duodenal conditions.

In a 2017 review, the authors concluded that all currently available PPIs are effective, and there are only small pharmacological differences in their use.

Pack photo of generic omeprazole 1omg capsules

Generic omeprazole

Lower cost generic omeprazole 10mg is also available. Generic medicines work in the same way and contain the same quantity of the active ingredient but are usually lower cost than brand-name medicines.

How does omeprazole relieve acid reflux/indigestion?

The cells which line your stomach, produce acid, using a specific biochemical process known as a 'proton pump'. Omeprazole stops the biological action of these pumps – and hence it is called a 'proton pump inhibitor' (PPI). Symptoms such as acid reflux and heartburn are reduced, because the stomach contents have lowered acidity.

Omeprazole is also effective, when combined with antibiotics, in treating H. Pylori. This is a bacterium sometimes found in the stomach, and associated with the development of gastritis, gastric and duodenal ulcers, and gastric cancer.

How to take Losec (omeprazole)

  • Take one 10mg capsule twice a day.
  • Initially, one capsule in the morning, an hour before food if possible.
  • Swallow capsules whole, with a glass of water. They should not be chewed or crushed.
  • If you have trouble swallowing, open the capsule and stir the contents into a small glass of non-carbonated water, or fruit juice. Then drink the entire contents of the glass within 30 minutes.

Who might be suitable for omeprazole?

Omeprazole is licensed to treat adults, aged over 18, with:

  • Duodenal and gastric ulcers, treatment and prevention
  • H. Pylori infection
  • Reflux esophagitis, treatment and prevention – commonly known as acid reflux/heartburn
  • Gastro-esophaeal reflux disease (GORD)
  • Zollinger Ellison Syndrome

How soon is omeprazole effective?

It may take 1-2 days to notice an effect from omeprazole. For best effects follow the instructions carefully on how to take it – see above or read the patient leaflet supplied in packs.

Who is not suitable for omeprazole?

During treatment with omeprazole, if symptoms develop such as unintended weight loss, vomiting, blood in the vomit, or dark, tarry stools you must seek urgent medical attention.

Omeprazole should not be taken with atazanavir, an anti-HIV drug.

What are the most common side effects of omeprazole?

Most common side effects (1 in 10 users)

  • Headache
  • Abdominal pain
  • Constipation
  • Diarrhoea
  • Flatulence
  • Nausea/vomiting

Uncommon side effects (1 in 100 users)

  • Difficulty sleeping
  • Dizziness
  • Pins and needles
  • Vertigo
  • Abnormal liver function tests
  • Skin rashes
  • Swelling

Rare side effects (1 in 1,000 users)

  • Low red/white cell count
  • Low sodium levels
  • Agitation
  • Confusion
  • Depression
  • Blurred vision
  • Dry mouth
  • Gastrointestinal candidiasis
  • Alopecia
  • Photosensitivity
  • Kidney disease
  • Sweating

Very rare side effects (1 in 10,000 users)

  • Abnormal white cells/red cells (agranulocytosis, pancytopenia)
  • Hallucinations
  • Liver failure
  • Severe skin disease
  • Enlarged breasts in men

Are there any drugs which might interact with omeprazole?

Omeprazole may lead to a decrease or an increase in the levels of certain drugs in your blood stream.

Omeprazole may lead to a decrease in certain drug levels in your blood stream:

  • Nelfinavir and atazanavir anti-HIV drugs
  • Clopidogrel – antiplatelet drug
  • Posaconazole, erlotinib, ketoconazole and itraconazole, antifungals

Omeprazole may lead to an increase in certain drug levels in your blood stream:

  • Saquinavir and ritonavir anti-HIV drugs
  • Tacrolimus – an immunosuppressant drug
  • Methotrexate – a chemotherapy drug

Some drugs may lead to a decrease or an increase of omeprazole in the blood stream.

Drugs which may decrease omeprazole levels:

  • Rifampicin - an anti-TB drug
  • St John's Wort - a herbal remedy

Drugs which may increase omeprazole levels:

  • Clarithromycin and voriconazole - antifungals

Any special warnings/precautions for use?

The following have been reported with long term use of omeprazole:

  • Low magnesium levels. Symptoms include fatigue, delirium, convulsions and cardiac arrhythmias. Periodic checks of blood magnesium levels are recommended.
  • Possible increase in the risk of fractures at the hip, wrist and spine, hence patients are recommended to follow national guidelines for prevention and treatment of osteoporosis, and to have an adequate intake of calcium and vitamin D.
  • Reduced absorption of vitamin B12.
  • A rare condition 'subacute cutaneous lupus erythematosis' (SCLE). If you develop a skin rash on sunlight exposed areas, always consult your doctor promptly.
  • As Losec contains lactose, it is not suitable for patients with galactose intolerance.
  • A slightly higher risk of gastroenteritis such as Campylobacter and Salmonella.
  • Possible dizziness, visual disturbances, and muscular weakness - if affected do not drive or operate heavy machinery.

Is omeprazole safe in pregnancy and/or breastfeeding?

You must discuss this with your doctor as no medication should be taken in pregnancy unless absolutely necessary. However, no adverse effects have been noted, and omeprazole may be taken in pregnancy and breastfeeding if you are advised to do so.

When would taking omeprazole become an emergency?

If you have any symptoms or signs suggestive of an acute allergic reaction (anaphylaxis), you must get help immediately by phoning 999.

Symptoms/signs of an acute allergic reaction include:

  • Difficulty breathing, tight chest, wheezing
  • Swelling of the face, lips and tongue
  • Skin rash – urticaria/hives
  • Confusion/collapse/unconsciousness

For more information see NHS - Anaphylaxis.

Patient Information Leaflet

Illustration of patient leaflet from medicine packet

The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine and must be read before taking the medicine. It is written for patients and gives information about taking or using a medicine.

Losec Patient Information Leaflet

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Authored 18 January 2019
by Dr Tony Steele, MB ChB

Reviewed 18 January 2019 by Dr B. Babor, Dr A. Wood, Dr P. Hunt

Last updated 19 February 2019

References
NHS - Omeprazole
AstraZeneca, 2017, Losec Capsules: Patient Information Leaflet, accessed 09 January 2019
AstraZeneca, 2017, Losec Capsules: Summary of Product Characteristics, accessed 09 January 2019
Strand, Kim, Peura, 2016, Gut Liver: 25 Years of Proton Pump Inhibitors: A Comprehensive Review, accessed 09 January 2019

Product reviews

Omeprazole rated 4.5/5 in 4 product reviews

See over 18,000 service reviews of Dr Fox

Losec

Very good for problems with stomake

19/01/2019 12:30
Anonymous Verified

Losec

Works very quickly to stop painful acid reflux

26/06/2017 13:18
Anonymous Verified

Losec

Not a bad product.

18/06/2017 11:16
Anonymous Verified

Losec

Seems to do the job, my stomach pains and reflux has got much better after 4 or 5 days .

16/09/2016 13:59
R. Humphreys Verified

More Omeprazole reviews

The order process

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