New Spedra (avanafil) tablets to treat erectile dysfunction available in 50mg, 100mg, and 200mg strengths.

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How to buy online

  1. Read medical information about erectile dysfunction
  2. Answer medical questions to check for eligibility
  3. Reviewed by doctors - posted from NHS pharmacy

Spedra (avanafil) is a newly licensed drug for the treatment of erectile dysfunction (July 2013).

Spedra is known as a PDE5 inhibitor and works in a similar way to Viagra/sildenafil, Cialis, and Levitra, which are also PDE5 inhibitors.


Tablet type4 tablets8 tablets16 tablets
Spedra 50mg£16.50£28.00£49.50
Spedra 100mg£19.50£37.00£68.00
Spedra 200mg£29.50£54.50£98.00

Prescription issued online - small prescription fee per order.

Compare prices: Dr Fox prices are 25%-50% lower cost than other online clinics.

Prescription fees

Dr Fox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.

Prescriptions are issued by our doctors online and sent electronically to our pharmacy.

If you have your own private paper prescription please post to our pharmacy (details).

Dr Fox prices are 25%–50% lower than other UK online clinics.

Order valuePrescription fee
up to £10£1.00
up to £20£3.00
up to £50£5.00
up to £100£8.00
over £100£10.00
Prices of Spedra from UK online clinics (22 May 2014). ** Oxford Online Pharmacy prices include £25 prescription fee. Qualifying notes
*Dr Fox adds a small prescription fee not included in table above.
  1. The prices shown are listed by the online clinics named after a customer first enters consultation information and is offered prescriptions. It is possible these clinics may have special offers or lower prices for repeat supplies.
  2. Prices may change and are, to the best of our knowledge, accurate on the date stated.
  3. Dr Fox does NOT claim to provide a superior service to any of the online clinics listed. All the clinics listed, as far as we can tell, comply with all regulation and, as far as we can tell, operate to high ethical standards.
  4. Dr Fox adds a small prescription fee not included in the table (between £1 and £10 depending on value of the order).
  5. To amend the information in this table please contact us
  6. The prices listed in the table do not identify the cost of prescription medicine as online clinics charge a single fee to cover services which includes advice, consultations, prescriptions and dispensing and supply of treatments.
  7. Viagra lost its exclusive UK patent 21 June 2013 allowing generic versions of sildenafil to be supplied legally in the UK.
MedicationDr Fox*The Online ClinicOxford Online Pharmacy**Pharmacy2U
Spedra 50mg x 4£16.50£49.95£38.50£35.00
Spedra 50mg x 8£28.00£79.95£49.50£55.00
Spedra 50mg x 16£49.50£109.95£74.00£104.50
Spedra 100mg x 4£19.50£59.95£42.50£35.00
Spedra 100mg x 8£37.00£89.95£57.50£55.00
Spedra 100mg x 16£68.00£149.95£90.00£104.50
Spedra 200mg x 4£29.50£79.95£52.10£43.00
Spedra 200mg x 8£54.50£129.95£74.10£75.00
Spedra 200mg x 16£98.00£199.95£123.20£142.50
UK Delivery£2.90included£2.95/free over £40£3.49/free over £40

Delivery charges

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About Spedra

Spedra (avanafil) is a newly licensed (July 2013) drug from Menarini to treat erectile dysfunction.

Spedra works in a similar way to Viagra/sildenafil, Cialis and Levitra.

Fake and genuine Spedra

There is an active illegal market in erectile dysfunction treatments. Men can ensure they receive only genuine medication and get proper advice by seeing a doctor face-to-face or by using websites registered in the UK with the Care Quality Commission, where medicine is supplied from UK registered pharmacies.

Alternative treatment

Cialis, Viagra/sildenafil, and Levitra are alternative tablet treatments for erectile dysfunction and are also available to buy in various strengths and pack sizes after completing the same medical consultation.

Dr Fox also supplies Vitaros cream, a non-tablet treatment for ED.

Taking Spedra

Tablets should be swallowed whole. If taken on an empty stomach Spedra is likely to be most active after 15 to 30 minutes, and is likely to remain active for a period 4 or more hours.

If taken on a full stomach, absorption is likely to be delayed up to 1.5 hours or more.

As with most erectile dysfunction treatment, Spedra supports natural erections. Sexual stimulation and normal foreplay are required for treatment to work. Without it, the effects of a tablet simply wear off over a few hours.


The usual starting dose is a single 100mg tablet, with subsequent doses being adjusted depending on the success of treatment. The maximum dose is a single 200mg tablet, the minimum single dose is one 50mg tablet.

No dose reduction is required for age, although study information is not available for men over 70 years.

Spedra tablets should not be taken within 36 hours of other erectile dysfunction medication.

Spedra dosage

Spedra 50mg tablets

Spedra 50mg

Reduced dose when 100mg starting does is highly effective.

Spedra 100mg tablets

Spedra 100mg

Starting dose recommended for most men taking for first time.

Spedra 200mg tablets

Spedra 200mg

Higher strength dose for when 100mg provides unsatisfactory results.

Consulting a doctor

All men taking treatment for erectile dysfunction should inform their GPs. Erectile dysfunction can be caused by conditions such as high blood pressure or diabetes, and these should be tested for. Men who are experiencing emotional distress, depression or relationship difficulties should see their GPs for support and advice.

Effectiveness of Spedra

Studies show approximately 50% of men taking Spedra report success, with higher doses producing better results. In the general population with ED, the mean percentage of attempts resulting in successful intercourse was approximately 47%, 58%, and 59% for the 50mg, 100mg, and 200mg avanafil groups, respectively, compared to approximately 28% for placebo.


Spedra is for men only, and should not be taken by women. Currently there is no data on sperm quality for men taking Spedra for erectile dysfunction, although no effects on sperm were found in healthy volunteers who took a single dose of Spedra. No significant effects on fertility have been found in men taking other similar medications (PDE5 inhibitors).

Side effects of Spedra

As with any medication, side effects are possible, although these rarely require cessation of treatment. The commonest side effects are headache, flushing, nasal and sinus congestion and back pain. A full list of Spedra side effects can be found in the manufacturer's patient information leaflet included in packs of Spedra tablets.

If men notice any of the following serious side effects, they need urgent medical treatment:

  • an erection that will not go away (priapism). If you get an erection that lasts more than 4 hours, this must be treated as soon as possible or lasting damage can happen to your penis (including not being able to get erections).
  • blurred vision.
  • sudden decrease or loss of vision in one or both eyes.
  • sudden decrease or loss of hearing (sometimes you may also feel dizzy or have ringing in your ears).

Coexisting medical conditions

Spedra is suitable for most men, but not all. Men who have a weak heart, recent stroke or reduced exercise tolerance should not take Spedra. Other medical conditions are listed in the manufacturer's patient information leaflet.

Checks for suitability are carried out during the online consultation at Dr Fox.

Interacting medications

Some prescription and non-prescription drugs interact with Spedra. Nitrates, used to treat angina (heart pain) and heart failure, increase the likelihood of low blood pressure. Some men use short acting inhaled nitrates, known as poppers, as a stimulant, and risk significant low blood pressure.

Other interacting medications could increase or decrease the effectiveness of Spedra. These interacting drugs are listed in the manufacturer's patient information leaflet and are checked for in online consultation.

Effects on ability to drive and use machines

Spedra has minor influence on the ability to drive and use machines. As dizziness and altered vision were reported in clinical trials with avanafil, patients should be aware of how they react to Spedra before driving or using machines.

Patient information leaflet – Spedra

The 'Patient Information Leaflets' supplied with medication must be read before taking tablets.

Spedra Patient Information Leaflet

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The order process

Answer short medical questionnaire

Choose treatment, register, and pay

Doctor issues prescription online

Medicine posted direct from pharmacy

Product reviews

Spedra rated 7.29/10 in 17 product reviews

See over 5,600 service reviews of Dr Fox

Good with no problems

20/10/2016 02:02
Anonymous Verified

Works well and no stomach issues.

03/10/2016 09:07
Anonymous Verified

Good mild product.

01/10/2016 15:35
Anonymous Verified

very good i have found

20/09/2016 05:16
Anonymous Verified

quite good

18/09/2016 12:07
Anonymous Verified

good product

14/09/2016 14:45
Anonymous Verified

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