Epiduo gel is a topical treatment for acne containing a retinoid and a peeling agent.

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How to buy online

  1. Read medical information about acne treatment
  2. Answer medical questions to check for eligibility
  3. Reviewed by doctors - posted from UK pharmacy


Acne treatmentQuantityCost
Epiduo gel (benzoyl peroxide 2.5% and adapalene 0.1%)45 grams£26.20
Epiduo gel (benzoyl peroxide 2.5% and adapalene 0.1%)90 grams (2 x 45 grams)£46.00
Epiduo gel (benzoyl peroxide 2.5% and adapalene 0.1%)135 grams (3 x 45 grams)£69.00

Prescription issued online - small prescription fee per order.

Prescription fees

Dr Fox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.

Prescriptions are issued by our doctors online and sent electronically to our pharmacy.

If you have your own private paper prescription please post to our pharmacy (details).

Dr Fox prices are 25%–50% lower than other UK online clinics.

Order valuePrescription fee
up to £10£1.00
up to £20£3.00
up to £50£5.00
up to £100£8.00
over £100£10.00

Delivery charges

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About Epiduo

Epiduo gel is an acne treatment which combines the active ingredients adapalene and benzoyl peroxide. It is applied once daily to acne affected areas, usually in the evening.

Adapalene belongs to a group of medicines know as retinoids and works in various ways to unblock pores and reduce acne. Benzoyl peroxide reduces bacteria on the surface of the skin and softens and peels the surface layers. The combination is likely to be more effective than either agent used on its own.

Other acne treatments

Benzoyl peroxide is available from pharmacies in various strengths as a non-prescription medicine and in combination with the antibiotic clindamycin in the prescription medicine Duac. Prescription only Differin cream and gel contains the adapalene as single agent product (not combined with other active ingredients).

Alternative topical and antibiotic tablets (lymecycline) for acne are available online through the acne treatment page.

It is usually preferable to use only one type of topical treatment (cream, gel, solution) at the time. Where different topical treatments are used at the same time, they should be applied at different times of day. Topical treatments should usually be used for at least 8 weeks. If there is no improvement after 8 weeks treatment should be changed. Successful treatments can be continued long term, although they may become less effective with time, particularly treatments containing antibiotics. If acne has resolved, treatment can be stopped, to be restarted later, if required.

Side effects and cautions

Not suitable for children under 9 years and is available online from Dr Fox with other acne treatments only to over 18s.

Epiduo commonly (in more than 1 in 10) makes skin dry and sensitive. This may lead to reddening and scaling. If this is significant the frequency of applications should be reduced, or in some cases treatment may need to be stopped. It is a good idea to try a test patch before applying the gel to larger areas and when starting treatment use on alternate days for the first week.

Other side effects are less common, and include itching and increased sensitivity to sun, and other rarer skin symptoms.

Epiduo should not be used by women who are pregnant or who are at risk of becoming pregnant. The gel can be used by women who are breast feeding as long as it is not applied to the chest.

Epiduo gel can stain or bleach clothing.

Avoid contact with eyes, inner nose or mouth. Wash hands after use.

Further information

Visit the manufacturer's (Galderma) website at www.epiduo.co.uk.

Patient information leaflet

The 'Patient Information Leaflet' supplied with the gel must be read before use.

Epiduo Gel Patient Leaflet

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Authored 19 November 2015
by Dr Tony Steele, MB ChB

Reviewed 18 November 2016 by Dr B. Babor, MB ChB

Last updated 9 February 2017

The order process

Answer short medical questionnaire

Choose treatment, register, and pay

Doctor issues prescription online

Medicine posted direct from pharmacy

Customer reviews

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