Genital Herpes

Genital Herpes advice and treatment with Aciclovir 400mg tablets available to buy online from our UK registered pharmacy.

Read medical information and answer medical questions to buy treatment online.

Medication available


All medicine supplied is UK licensed.

Aciclovir 400mg

Aciclovir 400mg

1-2 courses from £8.95
& 6-12 month suppression

Buy treatment


Aciclovir 400mg15 tablets (1 course of treatment)£8.95
Aciclovir 400mg30 tablets (2 courses of treatment)£13.95
Aciclovir 400mg168 tablets (3 months suppressive treatment)£29.20
Aciclovir 400mg336 tablets (6 months suppressive treatment)£49.40

Price match guaranteePrice match guarantee
Prescription issued online - small prescription fee per order.

Compare prices: Dr Fox prices are 25%-50% lower cost than other online clinics.

Prescription fees

Dr Fox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.

Prescriptions are issued by our doctors online and sent electronically to our pharmacy.

Order valuePrescription fee
up to £10£1.00
up to £20£2.00
up to £40£3.00
over £40£4.00

If you have your own private or NHS paper prescription please post to our pharmacy (details).

Dr Fox prices are 25%–50% lower than other UK online clinics.

Comparative costs of aciclovir genital herpes treatment from UK online clinics (07 April 2021) - qualifying notes
*Dr Fox adds a small prescription fee not included in table above.
  1. The prices shown are listed by the online clinics named after a customer first enters consultation information and is offered prescriptions. It is possible these clinics may have special offers or lower prices for repeat supplies.
  2. Prices may change and are, to the best of our knowledge, accurate on the date stated. All products in stock and new condition.
  3. Dr Fox does NOT claim to provide a superior service to any of the online clinics listed. All the clinics listed, as far as we can tell, comply with all regulation and, as far as we can tell, operate to high ethical standards.
  4. Dr Fox adds a small prescription fee not included in the table (between £1 and £4 depending on value of the order).
  5. To amend the information in this table please contact us
  6. The prices listed in the table do not identify the cost of prescription medicine as online clinics charge a single fee to cover services which includes advice, consultations, prescriptions and dispensing and supply of treatments.
  7. Where services include free delivery this is using the slowest delivery option available. Dr Fox uses Royal Mail Tracked 24.
MedicationDr Fox*ZavaSuperdrugSimple PharmacyLloydsIndependent Pharmacy
Aciclovir 400mg (1 course)£8.95£19.95£20.00£14.95£20.00£19.99
Aciclovir 400mg (2 courses)£13.95£24.95£25.00£19.95£25.00£31.98
Aciclovir 400mg (3 month course)£29.20£49.00£49.00£34.95£45.00£48.00
UK delivery£2.90includedincluded£3.20included£2.95

Delivery charges

UK delivery only: £2.90 per consultation via Royal Mail 24 Signed For (1-3 working days with tracking).

Parcel forwarding services are not permitted. Use only UK home or work delivery address.

Returns and refunds - unwanted items can be returned within 14 working days for a full refund.

Medical information

Written and reviewed by a team of doctors. Dr Fox is regulated by the CQC & GPhC.

If you have previously been diagnosed with genital herpes, and you are confident that you recognise the symptoms of repeat outbreaks, you can request treatment from Dr Fox pharmacy.

If you are aged under 18 please contact your GP or a local sexual health clinic for testing and treatment:

Diagnosis and check-up before treatment

Treatment with aciclovir

A 5-day course of aciclovir tablets will typically reduce the duration of genital herpes sores by one or two days. It also reduces severity of symptoms and infectiousness. If taken early enough, aciclovir may prevent sores from breaking open. A course of aciclovir will not prevent future outbreaks. Aciclovir cream is not recommended for treatment of genital herpes as it offers minimal benefit.

Suppression with aciclovir

If attacks are frequent (six or more attacks per year) guidelines recommend considering suppressive antiviral treatment. This involves taking aciclovir 400mg twice a day continuously for 6 months and up to a maximum of 12 months. Be aware you may get an outbreak 4-5 days after stopping long-term treatment. This is not a sign you will start to have repeated outbreaks. However if you have 2 or more reoccurrences on stopping then you can consider restarting suppressive treatment.

If breakthrough recurrences occur during suppressive treatment please notify your GP or visit a sexual health clinic.

Is herpes infectious?

When herpes sores are open and active, the virus is more infectious, however if you have the virus it can be spread to others even when you don't have sores. Using condoms provides some protection from transmission, but this protection is not 100% effective. Spread can still take place.

There is currently no genital herpes vaccine.

The following steps will help to reduce infection:

  • Using condoms for all sexual contact, including oral and anal sex. Avoid all sexual contact if you or your partner have blisters or sores, or other signs that a herpes sore is developing.
  • Avoid contact with blisters and sores - wash your hands if this occurs.
  • Avoid sharing sex toys and use them with a condom.
  • Managing stress - a common trigger for an outbreak.

Aciclovir dosage

Repeat genital herpes

Start treatment early, preferably in the first 24-48 hours of a new sore. Take one 400mg tablet three times daily 8 hours apart for 5 days. 15 tablets is enough for one course of treatment.

Suppression of genital herpes

Take one 400mg tablet twice a day 12 hours apart for a minimum of 6 months. Can be taken for up to 12 months, then a trial stopping treatment is advised.

Swallow tablets whole with plenty of fluids, or dissolve in water. Can be taken with or without food. Seek medical advice if treatment is not effective or there are new symptoms or side effects. It is important to drink plenty of water whilst taking aciclovir, and to avoid alcohol.

Please note: The dose instruction in the patient information leaflet supplied with the tablets is different from the instruction on the packet - follow the prescription instruction label on the box. Tablets will be supplied in blank boxes of 15 or 30 tablets, except for suppressive treatment which is supplied in original medicine boxes of 56 tablets.

The dosage for cold sore treatment is different to genital herpes treatment.

Can anyone take aciclovir?

People over 65 years, those diagnosed with kidney disease (impaired renal function), some neurological conditions, and women who are pregnant or breastfeeding may not be able to take aciclovir. Checks are carried out during the online consultation and advice is given. Dr Fox pharmacy supplies medicine only to adults (over 18s).

If you experience a bout of herpes during pregnancy or while breastfeeding, visit your doctor to discuss treatment options. Aciclovir should not interfere with contraception.

Aciclovir tablets and other medication

People taking the following medications should consult a doctor or pharmacist before taking aciclovir:

  • Probenecid (used to treat gout).
  • Cimetidine (used to treat stomach ulcers).
  • Mycophenolate mofetil (used to stop your body rejecting transplanted organs).
  • Ciclosporin (an immunosuppressant drug).
  • Theophylline (used in asthma and other breathing problems).
  • Zidovudine (used in HIV infection).

Side effects of aciclovir

Like all medicines, aciclovir can cause side effects, although not everybody gets them.

If you have an allergic reaction (may affect up to 1 in 1,000 people) stop taking aciclovir 400mg tablets and see a doctor straight away.

Common side effects include headache, feeling dizzy or sick, diarrhoea, stomach pains, rash, skin reaction after exposure to light (photosensitivity), fatigue, and fever.

See the patient information leaflet for further details.

Buy treatment

Dr Fox supplies genital herpes medication on prescription - you are required to answer a short medical questionnaire before your order can be completed.

Dr Tony Steele

Authored 26 February 2020 by Dr Tony Steele
MB ChB Sheffield University 1983. Former hospital doctor and GP.

Reviewed by Dr A. Wood, Dr C. Pugh, Dr B. Babor, Dr P. Hunt
Last reviewed 07 April 2021
Last updated 17 January 2022


  1. Medical questions
  2. Choose treatment
  3. Complete order

Answer medical questions to order(genital herpes)

Have you read the medical information on aciclovir for genital herpes?

Read the medical information.

Have you been diagnosed with genital herpes?

  • People with genital sores and other symptoms of sexually transmitted disease must have had a full medical assessment before obtaining treatment online.
  • New and changing symptoms need investigation.
  • Aciclovir only treats herpes virus infections, NOT other sexually transmitted diseases.

Have you been diagnosed with significant kidney disease (renal impairment)?

  • Please check with your doctor, if you are not sure
  • Renal impairment is part of the ageing process and people over 65 should check with their GP.

Have you been diagnosed with reduced immunity from any cause?

For instance you have:

  • Had a bone marrow transplant or low white blood cell count.
  • Been diagnosed with a neurological abnormality or any condition leading to permanently low oxygen levels.

Note: most people who are troubled with genital herpes have normal immune systems.

Are you taking any of the following medications?

  • Cimetidine (used to treat stomach ulcers).
  • Probenecid (used to treat gout).
  • Mycophenolate mofetil (used to stop your body rejecting transplanted organ).
  • Ciclosporin or tacrolimus (immunosuppressant drugs). Your doctor may monitor your kidney function.
  • Theophylline (used in asthma and other breathing problems).
  • Zidovudine (used in HIV infection).

Are you pregnant or breastfeeding or likely to be at the time of taking aciclovir?

Are you aware that aciclovir works best to treat an attack when taken as soon as symptoms of sores start?

  • It is best to start treatment in the first 24-48 hours - it is reasonable to keep supplies at home in reserve.
  • The first symptoms are usually pain and tingling at the site of the sore.
  • Herpes sores always break-out in the same places - sores in new places need investigation.

Are you aware genital herpes can be passed on to partners, particularly when sores are active and open?

Condoms provide significant protection from infection, but not 100% protection.

Are you aware treatment dose is one aciclovir 400mg tablet three times daily for five days or suppression dose is 400mg twice daily for up to 12 months?

  • This is the prescribed dose written on the label affixed to the packet, and differs from the patient information leaflet supplied with the tablets.
  • Please follow the instruction on the label affixed to the packet supplied.

Have you had an outbreak when taking suppressive treatment (aciclovir 400mg twice daily)?

If this is your first time ordering OR if you are ordering a treatment dose, answer 'No'.

Do you have any further medical information or questions?

Is there anything you do not understand or do you need further help?

Do the following apply to you?

  • The medication is for my own use and I will not share with anyone else
  • I will read the patient information leaflet supplied with the medication
  • I am over 18 and I agree to identity verification checks
  • I have completed this questionnaire myself and fully understand all the information
  • My responses are honest and accurate, and I understand that this is necessary for a safe medical assessment
  • I agree to the terms & conditions, privacy policy, & data sharing policy

The order process

Choose medication, register, and pay

Dr Fox issues prescription online

Pharmacy team post medication direct

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