Estriol 0.01% vaginal cream prices

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Estriol 0.01% vaginal cream is a low-dose vaginal oestrogen used to treat vaginal and urinary symptoms of the menopause. It contains estriol, a naturally occurring oestrogen, and is applied directly into the vagina using the supplied applicator.

Vaginal oestrogen works locally, with very little absorption into the bloodstream.

How does Estriol 0.01% vaginal cream work?

After the menopause, the body produces much less oestrogen. This can cause thinning and dryness of the vaginal tissues (vaginal atrophy), leading to symptoms such as dryness, soreness, itching, pain during sex, urinary symptoms, and recurrent infections.

Estriol applied directly to the vagina helps restore the vaginal lining, which can improve moisture, elasticity, and comfort. It can be used alone or alongside systemic (whole body) HRT.

As there is a larger volume of cream in each application dose of estriol 0.01% (5g) compared with estriol 0.1% cream (0.5g) and Blissel gel (1mg) this can be useful where dryness and soreness are particular issues.

How to use Estriol 0.01% vaginal cream

• Initial treatment: use once nightly for 2 weeks.
• Maintenance treatment: use twice weekly, spaced 3-4 days apart.

Using the applicator

1. Screw the applicator onto the tube.
2. Squeeze the tube to fill the applicator.
3. Remove the applicator from the tube.
4. Insert into the vagina (similar to a tampon).
5. Press the plunger to release the cream.
6. Wash the applicator in warm water, dry, and reuse.

If unable to use the applicator, or there is significant soreness at the entrance to the vagina and to the vulva, the dose of estriol 0.01% cream can be applied with a fingertip to these areas. Wash hands thoroughly after use.

When not to use Estriol 0.01% vaginal cream

You should not use this treatment if:

• You are allergic to estriol or any ingredient in the cream.
• You have a known allergy to peanuts or soya (contains peanut oil).

Estriol 0.01% vaginal cream cautions

Although vaginal oestrogen is absorbed only minimally into the bloodstream, manufacturers advise caution in women who have been told not to use systemic HRT. Doctors may still prescribe vaginal oestrogen where benefits outweigh risks.

Any unexplained vaginal bleeding after 3 months of use should be assessed by your GP.

Estriol 0.01% vaginal cream and other medicines

Vaginal oestrogen is very unlikely to interact with medicines taken by mouth or injection. Avoid using at the same time of day as other vaginal products.

Possible side effects of Estriol 0.01% vaginal cream

Side effects are unusual and usually mild. They may include:

• Local irritation or discomfort.
• Vaginal discharge.
• Headache or abdominal discomfort.

Stop using and seek medical advice if you develop:

• Signs of allergy.
• Jaundice (yellowing of the skin or eyes).
• Sudden high blood pressure.
• First-ever migraine-type headache.
• Symptoms of a blood clot.
• Pregnancy.

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Other information:

Vaginal dryness fact sheet
Urogenital problems fact sheet