Acid reflux / indigestion

Losec (Omeprazole) and Zantac (Ranitidine) for acid reflux / indigestion and heartburn. Medicine on prescription from UK pharmacy.

Read medical information and answer medical questions to buy treatment online.

Treatment available

Losec 10mg

Losec 10mg (omeprazole)

28-56 capsules from £14.50

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Zantac 150mg

Zantac 150mg (ranitidine)

30-60 tablets from £8.40

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Acid reflux/indigestion treatmentQuantityCost
Losec (Omeprazole) 10mg capsules28 capsules£14.50
Losec (Omeprazole) 10mg capsules56 capsules£23.10
Zantac (Ranitidine) 150mg tablets30 tablets£8.40
Zantac (Ranitidine) 150mg tablets60 tablets£14.40

Prescription issued online - small prescription fee per order.

Prescription fees

Dr Fox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.

Prescriptions are issued by our doctors online and sent electronically to our pharmacy.

If you have your own private or NHS paper prescription please post to our pharmacy (details).

Dr Fox prices are 25%–50% lower than other UK online clinics.

Order valuePrescription fee
up to £10£1.00
up to £20£3.00
up to £50£5.00
up to £100£8.00
over £100£10.00

Delivery charges

UK delivery only: £2.90 per consultation via Royal Mail 24 Signed For (1-3 working days with tracking).

Parcel forwarding services are not permitted. Use only UK home or work delivery address.

Medical information

Acid reflux, acid indigestion and heartburn

Acid reflux, heartburn and acid indigestion are used interchangeably. They are all terms describing the burning pain caused by stomach acid.

Acid produced in the stomach can travel up to the gullet and the back of the throat. This produces a burning sensation in the region of the breastbone and occasionally a taste of acid in the throat.

Dr Fox supplies two different strong acid suppressant medications for the treatment of reflux: Losec (Omeprazole) and Zantac (Ranitidine).

Frequency of acid indigestion

Almost everybody will experience acid indigestion from time to time. It can be brought on spicy food or by drinks such as wine or acid fruit juice. Most acid indigestion will settle with antacid tablets containing an alkali. These are the familiar chalky tablets or medicines.

Some people are prone to repeated episodes of acid reflux. For these people Losec (Omeprazole) or Zantac (Ranitidine) taken daily for few days will usually settle symptoms for a week or two at a time. Indigestion symptoms can usually be kept under control by taking a Losec (Omeprazole) or Zantac (Ranitidine) tablets on an as required basis.


GPs prescribe regular Losec (Omeprazole) or Zantac (Ranitidine) for people with severe or ongoing acid symptoms.

Losec is more effective at suppressing acid than Zantac. Losec suppresses acid for around 24 hours per dose, Zantac for 12 hours. Both will be effective in people who get only occasional acid reflux symptoms.

GPs normally investigate acid reflux symptoms when they are severe, are changing, or do not respond to simple antacid and acid suppressant treatments.

Medication and dosage

For people with mild or occasional symptoms Losec (Omeprazole) daily or Zantac (Ranitidine) twice daily for 4-5 days will settle the problem, usually for a few weeks at the time.

Where a short course of Losec (Omeprazole) or Zantac (Ranitidine) for 4-5 days does not control symptoms, or where a person's symptoms return immediately on stopping tablets, it is best to see a GP.

Losec (Omeprazole)

The starting dose of Losec is one 10mg capsule daily. This can be doubled to two 10mg capsules daily if symptoms are not controlled by the lower dose. Losec works best if taken daily for 4-5 days to settle symptoms down.

One or two 10mg Losec capsules daily can also be taken on an as required basis when symptoms flare up.

Zantac (Ranitidine)

Zantac is best taken at a dose of one 150mg tablet twice daily for 4-5 days to settle symptoms down.

Zantac 150mg tablets can also be taken once or twice daily on an as required basis when symptoms flare up.

Risk of taking strong acid suppressants (Losec or Zantac)

Zantac and Losec are widely used and safe medications. Both interact with a few prescription medication, most notably Warfarin and Phenytoin.

The main risk of taking either is the danger of masking the symptoms of a cancer in the stomach or gullet.

For this reason Losec (Omeprazole) or Zantac (Ranitidine) should only be taken after seeing a doctor face-to-face if the following apply.

Those aged 55 years or over:

  • With new onset of symptoms within the last year
  • Where symptoms are worsening or changing

People of any age with heartburn where there is:

  • Unintentional weight loss
  • Anaemia
  • Difficulty or pain on swallowing
  • Vomiting, particularly if there is blood in the vomit
  • Previous gastric ulcer or surgery
  • Jaundice

Those sufferers who have had to take an antacid or acid suppressor continuously for four or more weeks in order to control their symptoms.

Those who have taken an indigestion or heartburn remedy for two weeks with no relief of symptoms.

When to consult a doctor

If a person is not sure about their symptoms or has never seen a doctor about acid problems it is best to see a doctor face-to-face.

If symptoms improve with treatment, but come back when it is stopped, your regular doctor may want to test for H. Pylori, which is a bacterial infection of the stomach associated with reflux symptoms. If the H. Pylori test is positive, a course of antibiotic eradication treatment is usually prescribed.

Some medication can produce irritation in the stomach and gullet, most notably anti-inflammatory medications. Where a person is taking these drugs they should see their GP to discuss possible alternatives.

Anybody taking regular medication should let their regular doctor know they are taking occasional Losec (Omeprazole) or Zantac (Ranitidine). The GP may want to monitor the regular medication or adjust the dosages.

Interactions and contraindications

Losec (Omeprazole) is well-tolerated and side effects generally mild and reversible. Headache, diarrhoea, nausea, abdominal pain and rash are among adverse side effects reported with Omeprazole.

Similarly Zantac (Ranitidine) does not normally produce sided effects. Headache, feeling dizzy and diarrhoea are the most frequently reported side effects.

Buy treatment

Dr Fox supplies Losec and Zantac on prescription – you are required to answer a short medical questionnaire before your order can be completed.

Authored 30 June 2010
by Dr Tony Steele

Reviewed 04 January 2017 by Dr B. Babor, MB ChB

Last updated 22 February 2018

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Have you read the medical information?

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Are you aware this service supplies Zantac and Losec for occasional use only?

People requiring more than four 10mg Losec capsules or six 150mg Zantac tablets per week on a regular basis should consult a GP.

Do any of the following apply to you?

Aged 55 years or over:

  • With new onset of symptoms within the last year
  • Where symptoms are worsening or changing

People of any age with heartburn where there is

  • Unintentional weight loss
  • Anaemia
  • Difficulty or pain on swallowing
  • Vomiting, particularly if there is blood in the vomit
  • Previous gastric ulcer or surgery
  • Jaundice
  • Abdominal lump
  • Persistent pain

Are you aware all acid symptoms should settle with 5 or fewer days of treatment?

Losec 20mg daily (two 10mg tablets daily) or Zantac 150mg one tablet twice daily for 5 days should settle all symptoms for at least a few days.

Are you aware if symptoms are not controlled by taking Losec or Zantac 2-3 times weekly a doctor should be consulted?

If symptoms are not controlled by taking Losec or Zantac 2-3 times weekly a doctor should be consulted.

Are you aware worsening or changing symptoms require a review by a GP?

Are you planning to order Zantac (ranitidine) and take any of the following medications?

Please answer 'No' if ordering Losec (omeprazole)

  • Non-Steroidal Anti-Inflammatory (NSAID) medicines - for pain and inflammation
  • Lidocaine - a local anaesthetic
  • Propranolol, procainamide or n-acetylprocainamide - for heart problems
  • Diazepam - for worry or anxiety problems
  • Phenytoin, for epilepsy
  • Theophylline - for breathing problems (asthma)
  • Warfarin - for thinning your blood.
  • Glipizide - for lowering blood glucose
  • Atazanavir or delaviridine - for treating HIV infection
  • Triazolam - for insomnia
  • Gefitnib - for lung cancer
  • Ketoconazole - an anti fungal medicine, sometimes used for treating thrush

Are you planning to order Losec (omeprazole) and take any of the following?

Please answer 'No' if order Zantec (ranitidine)

  • Atazanavir - for HIV; Ketoconazole, itraconazole or voriconazole - for fungal infections
  • Diazepam for treat anxiety, relax muscles or in epilepsy
  • Phenytoin - for epilepsy
  • Medicines that are used to thin your blood, such as warfarin
  • Digoxin - used for heart problems
  • Tacrolimus - in organ transplants

Do the following apply to you?

The order process

Answer short medical questionnaire

Choose treatment, register, and pay

Doctor issues prescription online

Medicine posted direct from pharmacy

Customer reviews

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