Cytisine tablets (1.5mg) can help reduce nicotine cravings during stop smoking attempts. Available to buy online from Dr Fox pharmacy.

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Buy Cytisine online in UK

How to order cytisine 1.5mg tablets online for UK delivery:

  1. Read medical information about cytisine
  2. Answer medical questions to check for eligibility
  3. Reviewed by doctors - posted from UK pharmacy (Royal Mail Tracked 24 service)

Cytisine prices

Prices of cytisine tablets from Dr Fox (in stock)
Item Quantity Cost
Cytisine 1.5mg 100 tablets (25 day course) £145.00

Price match guarantee
Prescription issued online - small prescription fee per order.

Compare prices: Dr Fox prices are 25%-50% lower cost than other online clinics.

Prescription fees

Dr Fox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.

Prescriptions are issued by our doctors online and sent electronically to our pharmacy.

Order value Prescription fee
up to £10 £1.00
up to £20 £2.00
up to £40 £3.00
over £40 £4.00

If you have your own private paper prescription please post to our pharmacy (details).

Dr Fox prices are 25%–50% lower than other UK online clinics.

Prices of cytisine 1.5mg tablets from UK online clinics (07 May 2024) - qualifying notes
*Dr Fox adds a small prescription fee not included in table above.
  1. The prices shown are listed by the online clinics named after a customer first enters consultation information and is offered prescriptions. It is possible these clinics may have special offers or lower prices for repeat supplies.
  2. Prices may change and are, to the best of our knowledge, accurate on the date stated. All products in stock and new condition.
  3. Dr Fox does NOT claim to provide a superior service to any of the online clinics listed. All the clinics listed, as far as we can tell, comply with all regulation and, as far as we can tell, operate to high ethical standards.
  4. Dr Fox adds a small prescription fee not included in the table (between £1 and £4 depending on value of the order).
  5. To amend the information in this table please contact us
  6. The prices listed in the table do not identify the cost of prescription medicine as online clinics charge a single fee to cover services which includes advice, consultations, prescriptions and dispensing and supply of treatments.
  7. Where services include free delivery this is using the slowest delivery option available. Dr Fox uses Royal Mail Tracked 24.
Cytisine Dr Fox* Lloyds online doctor Oxford Online Pharmacy ASDA online doctor nowpatient
100 tablets £145.00 £162.99 £199.99 £200.00 £184.00
UK delivery £2.90 included £4.99 £3.50 included

Delivery charges

UK delivery only: £2.90 per consultation via Royal Mail Tracked 24 Signed For (1-3 working days with tracking).

Parcel forwarding services are not permitted. Use only UK home or work delivery address.

Returns and refunds - unwanted items can be returned within 14 working days for a full refund.

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About cytisine

  • Cytisine 1.5mg is a prescription-only tablet used reduce to nicotine cravings during quit smoking attempts.
  • 100 tablets is a standard course of treatment, taken over 25 days.
  • Cytisine is safe and effective, increasing stop smoking success by approximately 75% compared with placebo.
  • Evidence suggests that 25 days of cytisine treatment is as effective as nicotine replacement therapy but cytisine also weans you off nicotine.
  • Cytisine has no known serious side effects.
  • Read the patient leaflet for a full list of side effects, cautions, and interactions with other drugs.

How cytisine works

Tobacco contains nicotine. When you smoke, nicotine is absorbed through your lungs into your blood. When nicotine reaches your brain it stimulates the release of neurotransmitters including dopamine, which acts to cause feelings of pleasure, often leading to nicotine addiction.

When you stop smoking you no longer stimulate the production of dopamine and you may experience a variety of symptoms such as craving a cigarette, feeling restless, a change in mood, or trouble sleeping. For most people who stop smoking, these withdrawal symptoms are worse in the first few days to a couple of weeks, then they reduce in strength and frequency.

Cytisine works by attaching to some of the same receptors in the brain as nicotine, reducing the pleasurable feelings experienced when using nicotine-containing products. Cytisine increases the likelihood you will stop smoking by approximately 75% compared with placebo, but also allows a gradual reduction in nicotine dependence. Compared with nicotine replacement therapy, where the body remains addicted to nicotine, cytisine has the additional benefit of weaning you off nicotine.

Managing nicotine cravings and increased appetite

Cravings are powerful urges to smoke for which there may be triggers, e.g. stressors, situations where you would usually smoke, seeing others smoking. You are more likely to give in to cravings if your inhibitions are reduced, e.g. by drinking alcohol or using recreational drugs.

Nicotine can also reduce your appetite, therefore stopping smoking may inadvertently increase your appetite. If you choose to eat as an alternative to smoking, you may gain weight. Suggestions for keeping your hands and mouth busy are:

  • Have to hand a 'fiddle toy'.
  • Drink water if you are tempted to eat between meals which also keeps you hydrated.
  • Take a short walk or do 5 minutes exercise which also good for your general health.
  • Further information and advice: Manage Weight Gain After Quitting.

How to take cytisine

  • Each tablet contains 1.5mg of cytisine.
  • One pack of cytisine contains 100 tablets - a complete course of treatment (25 days).
  • Cytisine should be taken with water according to the schedule below.
  • Each day, following your 1st dose of cytisine, we suggest you set a reminder / alarm for the next dose.
  • Note: your quit smoking date should be no later than day 5. Continued smoking may worsen any treatment reaction.
  • If you miss a dose of cytisine you should not take a double dose to make up for it. You should just take the next dose as indicated.
Cytisine 25-day schedule of treatment to reduce nicotine cravings
Days of treatment Recommended dosing Maximum daily dose
From the 4th to the 12th day 1 tablet every 2.5 hours 5 tablets
From the 13th to the 16th day 1 tablet every 3 hours 4 tablets
From the 17th to the 20th day 1 tablet every 5 hours 3 tablets
From the 21st to the 25th day 1-2 tablets a day 2 tablets

An alternative version of the treatment schedule which you may find easier to follow (from the National Centre for Smoking Cessation and Training).

Cytisine summary and dosing guide

Does cytisine work 1st time?

Cytisine is likely to increase the chances you will quit smoking successfully by approximately 75% compared with placebo. The standard course of treatment is 25 days. If you don't manage to quit smoking on your first attempt, cytisine can be used again, but it is advised that you wait 2-3 months.

Improving your chances of quitting smoking

If you are mindful, notice your cravings, and find strategies to manage them that work for you, you are more likely to succeed in your quit smoking attempt. Here are some hints and tips for you to consider:

  • Make a quit plan - think ahead about ways you will manage your cravings if and when they happen. Choose a quit date, stick to it, and seek support from family, friends, and colleagues.
  • Know your triggers - cravings and thoughts about smoking can be triggered by the people you spend time with, the places you go, and the situations you encounter. Avoid your triggers, at least temporarily, after you quit to help lessen your cravings and give you time to build confidence and skills for remaining smoke free.
  • Distract yourself - practice mindfulness and remember your reasons for quitting. Quitting smoking is great for your health, the health of those around you, and your bank account! Calculate how much money you will save per week / per year and what you could spend your money on instead.
  • Get TXT message support - TXT the word CRAVE to 47848 to get 24/7 immediate support whenever you have a craving, or TXT QUIT to 47848 to sign up for SmokefreeTXT, a 6-8 week program of daily TXT message support, tips, and encouragement.
  • Try a quit smoking medication like cytisine. If nicotine withdrawal symptoms are difficult for you, prescription quit smoking medications or nicotine replacement therapy can make your symptoms easier to handle.
  • Use the free app – track your cravings and understand your smoking patterns with one of the apps.

If you don't manage to quit 1st time, or if you relapse, then try again having learned from your previous experience. To read more see Managing Nicotine Withdrawal.

Cytisine warnings and cautions

During the assessment process with Dr Fox you are required to complete a medical questionnaire to determine suitability.

Cytisine should not used if you have:

  • Hypersensitivity to cytisine or any of the non-active ingredients (mannitol, microcrystalline cellulose, magnesium stearate, glycerol dibehenate and hypromellose).
  • Unstable angina (chest pain due to reduced blood supply to the heart that occurs at rest and minimal exercise. Your GP or cardiologist should be able to advise if you are unsure).
  • Had a heart attack within the last 6 weeks.
  • A clinically significant abnormal heart rhythm. Your GP or cardiologist should be able to advise you if you are unsure.
  • Had a stroke within the last 6 months.
  • Are taking anti-tuberculosis drugs.
  • Are pregnant or breastfeeding.

Pregnancy, breastfeeding, & risk of pregnancy

The impact of cytisine on the effectiveness of oral contraceptives is unknown. If you are of childbearing age and wish to use cytisine, you should use contraception if you are having sexual intercourse. If you take tablet-form hormonal contraception, you should also use a secondary barrier method (e.g. condom).

Cytisine should not be used if you are pregnant or breastfeeding as the effects of cytisine on your baby are unknown.

Every cigarette contains more than 4,000 chemicals, many of which are dangerous. Smoking during pregnancy can restrict the essential oxygen supply, harming your unborn baby. In many areas of the UK there are specialist NHS services to assist pregnant women to stop smoking. It is highly advisable to speak to your midwife or doctor for advice. For more information see:

Cytisine cautions

If you are of childbearing age and wish to use cytisine, you should use contraception if you are having sexual intercourse. If you take tablet-form hormonal contraception, you should also use a secondary barrier method (e.g. condom) because the impact of cytisine on the effectiveness of oral contraceptives is unknown.

Cytisine should be taken with caution if you have:

  • Angina (ischemic heart disease) where your heart doesn't receive enough oxygen.
  • Heart failure.
  • Untreated high blood pressure.
  • Pheochromocytoma (a tumour in the adrenal glands).
  • A diagnosis of atherosclerosis (a build-up of fatty deposits in arteries which restricts blood flow).
  • Peripheral vascular disease (blood flow is restricted to areas other than the heart and brain).
  • Gastric or duodenal ulcer (stomach or small intestine ulcer).
  • Acid reflux disease.
  • Hyperthyroidism (overactive thyroid).
  • Diabetes.
  • Schizophrenia.

Dr Fox cannot supply cytisine if you have any of the above conditions. Please check with your regular doctor whether cytisine is suitable for you.

Please note: If you have a history of a mental health condition

Stopping smoking has been associated with worsening of underlying mental health illness. Developing a depressed mood may be symptomatic of nicotine withdrawal. This is rarely severe enough to include suicidal ideation or attempted suicide. If you have a history of psychiatric illness, it is strongly advised that you seek advice from your relevant health care professional before using cytisine or other quit-smoking medication.

Cytisine - interaction with other medicines

Cytisine should not be used with anti-tuberculosis drugs.

If you take theophylline (to treat asthma), clozapine (to treat schizophrenia) or ropinirole (to treat Parkinson's disease) it is particularly important you speak to your GP before taking cytisine, as your medication dose/monitoring schedule may need changing.

Dr Fox cannot supply cytisine if you take any of the above medications.

Please note: If you take theophylline, warfarin, or insulin, the effect of these medications may be altered if you simply stop smoking. It is therefore recommended that you seek advice from your usual GP regarding the need for dose adjustment.

If you take tablet-form hormonal contraception, you should also use a secondary barrier method (e.g. condom) while taking cytisine. This is because the impact of cytisine on the effectiveness of oral contraceptives is unknown.

If you use products containing nicotine, or continue to smoke while taking cytisine (beyond the first 5 days), you are more likely to experience adverse reactions.

Cytisine - possible side effects

Clinical studies and experience indicate that cytisine is well tolerated, however you may experience the following side effects:

  • Very common (may affect more than 1 in 10): change in appetite, weight gain, dizziness, irritability, mood changes, anxiety, high blood pressure, dry mouth, diarrhoea, rash, fatigue, sleep disorders, headaches, fast heart rate, nausea, change in taste, heartburn, constipation, vomiting, abdominal pain, muscle pain.
  • Common (may affect upto 10 in 100): difficulty concentrating, slow heart rate, abdominal distension, burning tongue, malaise.
  • Uncommon (affects upto 10 in 1,000): a feeling of heaviness in the head, decreased sex drive, excessive tears, shortness of breath, increased phlegm, excessive spit production, sweating, decreased skin elasticity, tiredness.

For a full list of side effects please read the manufacturer's cytisine patient information leaflet.


If you accidentally take more than the recommended dose of cytisine you may experience symptoms similar to nicotine overdose.

Mild symptoms are malaise (a general feeling of discomfort) and nausea.

More severe symptoms (usually associated with larger overdoses) include vomiting, palpitations (sensation of the heart beating due to an increased heart rate), changes in blood pressure, breathing problems, blurred vision, and convulsions (seizures/fits). If you develop any of these symptoms, you must seek immediate medical advice and stop taking cytisine.

Reporting of suspected adverse reactions

Most adverse reactions occur in the first few days of cytisine treatment but they usually resolve quickly.

If you suspect you have experienced a concerning adverse reaction to a medicine, reporting it allows the product to be monitored. You can report your suspicions of a safety concern or incident by using the MHRA Yellow Card scheme - also available from Apple App Store or Google Play Store.

Stopping taking cytisine

If you stop taking cytisine abruptly and you are no longer smoking (beyond day 5), you may experience the return of some nicotine-withdrawal symptoms such as mood change, irritability, sleep disturbance, and/or an urge to smoke. Symptoms can be minimised by gradual dose reduction to a stop, rather than stopping abruptly.

Please note that if you stop smoking without using cytisine, withdrawal symptoms may occur due to lack of nicotine from cigarettes.

Alternative stop smoking treatments

In the UK several treatments to help you to quit smoking are available in addition to cytisine.

Nicotine replacement therapy (NRT): transdermal patch, gum, lozenge, nasal spray, inhalator & mouth spray. Use of a longer-acting transdermal patch in combination with a faster-acting gum, lozenge, or inhalator is called 'combination NRT' and is more effective than using a single product. Used in approximately 15% of quit attempts in the UK. Available over the counter from pharmacies and some supermarkets.

Nicotine vapes (e-cigarettes) allow you to inhale nicotine in a vapour rather than smoke. They are generally more effective than NRT. People who use vapes to stop smoking are still experiencing the addictive effects of nicotine and therefore tend to continue to use them for months or years after stopping smoking tobacco. Used in approximately 35% of quit attempts in the UK. Available over the counter from pharmacies and some supermarkets.

Bupropion (Zyban) is licensed for use in the US as an antidepressant and as a stop smoking aid. Zyban is available only on prescription. Used in less than 1% of quit attempts in the UK.

Varenicline (Champix). Branded Champix is not currently available. Champix was withdrawn in the UK in 2020 due to manufacturing issues. The patent then expired and Pfizer (the company that developed it) has not yet reintroduced it. Generic varenicline is available from some providers on prescription but does not have a UK license so is supplied off label.

Dr Fox does not supply Zyban, NRT, or nicotine vapes. Dr Fox supplied Champix until it became unavailable.

For more information see the NHS Stop smoking treatments and Using e-cigarettes to stop smoking advice.

Cytisine FAQs

Can I use cytisine and nicotine replacement therapy (NRT) together?

This is probably best avoided as nicotine from NRT or nicotine vapes may lead to adverse reactions if they are used at the same time as cytisine.

Does the quit date have to be on day 5 of the dosing schedule, or can it be later?

Yes the quit date should be no later than day 5. Quitting after day 5 has not been fully researched and continued smoking may worsen any treatment reaction. You can however stop smoking before day 5, so to avoid abrupt nicotine withdrawal symptoms you could reduce cigarette use toward the day 5 cut-off.

What should I do if I smoke after the quit date?

Ideally continue with the quit attempt and keep taking the cytisine. Having a cigarette after your quit date is not a reason for stopping cytisine and starting smoking again. It is likely that cytisine will keep you on track with stopping smoking.

Is taking cytisine for longer than the 25 day course more likely to help me stop smoking on the first attempt?

The standard course of treatment is 25 days. Using it for up to 12 weeks may also be effective, but is not the current recommended treatment plan.

What should I do if I experience adverse side effects?

If you are worried about side effects it is best to consult with your doctor, but if they are mild and tolerable there is no reason to stop taking the cytisine. Most side effects get better or even disappear over a short time. Remember that stopping smoking in itself causes a range of withdrawal symptoms.

Can I take cytisine if I have a mental health condition?

Cytisine is not contra-indicated for people with mental health conditions. Dr Fox is unable to prescribe cytisine if you have a current psychiatric illness. This is because your usual healthcare provider may advise closer monitoring while you take cytisine, to ensure that it does not have a detrimental effect on your mental wellbeing.

Should I stop taking cytisine if I develop a low mood or feel depressed?

Stopping smoking has been associated with worsening of underlying mental health illness. Developing a depressed mood may be symptomatic of nicotine withdrawal. This is rarely severe. If you are concerned about your symptoms. It is recommended that you stop taking cytisine and seek advice from your usual GP.

Can I drink alcohol while taking cytisine?

It is OK to drink alcohol with cytisine, but please note that alcohol may reduce your inhibitions and you may be more likely to smoke. Cytisine may actually make you less inclined to drink alcohol.

Can I drive or operate machinery when taking cytisine?

Yes. Cytisine has no influence on your ability to drive or use machines.

Can I take a course of cytisine more than once?

Yes, if you don't manage to quit smoking the first time, or if you relapse, a repeat course of cytisine may be effective but you should leave 2-3 months before trying again.

Patient Information Leaflet

Illustration of patient leaflet from medicine packet

The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine and must be read before taking the medicine. It is written for patients and gives information about taking or using a medicine.

Cytisine Patient Leaflet

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Further information and support

GP surgeries, pharmacies, and local councils may provide access to a variety of stop smoking support services. Also:

Dr Jaime Tweedie

Authored 07 May 2024 by Dr Jaime Tweedie
MB ChB Leicester-Warwick Medical School 2004. NHS GP, urgent care, and CQC advisor experience. GMC no. 6101380

Reviewed by Dr C. Pugh, Dr A. Wood, Dr B. Babor
Last reviewed 07 May 2024
Last updated 17 May 2024
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