Potential interactions with other medicines
People taking medicines from the following list should consult with their regular doctor before taking Kwells or using Scopoderm patches.
These interactions may not be important. It is best to check.
Possible increased drowsiness
There may be an increased risk of drowsiness if Scopoderm patches or Kwells are used with medicine from the following list:
- antipsychotic medicines, eg chlorpromazine
- barbiturates, e.g. phenobarbital
- benzodiazepines, e.g. diazepam, temazepam
- sedating antihistamines, e.g. chlorphenamine, brompheniramine, hydroxyzine
- sleeping tablets, e.g. zopiclone
- strong opioid painkillers, e.g. morphine, codeine, dihydrocodeine
- tricyclic antidepressants, e.g. amitriptyline
Possible increase in other side effects
There may be an increased risk of side effects, such as dry mouth, blurred vision or difficulty passing urine, if Scopoderm patches or kwells are used in combination with other medicines, such as the following:
- antiarrhythmic medicines for irregular heartbeats, e.g. disopyramide, propafenone, quinidine
- antihistamines, eg promethazine, brompheniramine, chlorphenamine, diphenhydramine, triprolidine (some of these are often found in over-the-counter cough and cold remedies)
- antimuscarinic medicines for Parkinson's symptoms, e.g. procyclidine, orphenadrine, trihexiphenidyl
- antimuscarinic medicines for urinary incontinence, e.g. oxybutynin, trospium, tolterodine
- antipsychotics, e.g. chlorpromazine, clozapine, thioridazine
- antisickness medicines, e.g. meclozine, cyclizine
- antispasmodics, e.g. atropine, propantheline, hyoscine butylbromide
- MAOI antidepressants, e.g. phenelzine
- muscle relaxants, e.g. baclofen
- tricyclic antidepressants, e.g. amitriptyline, clomipramine.
If you experience a dry mouth as a side effect of this medicine you may find that medicines that are designed to dissolve and be absorbed from under the tongue, e.g. sublingual glyceryl trinitrate (GTN) tablets, become less effective. This is because the tablets do not dissolve properly in a dry mouth. To resolve this, drink a mouthful of water before taking sublingual tablets.
If taken with other 'anticholinergic' drugs there is a possible increase in the risk of side effects, especially dry mouth.