Cerelle

Cerelle contraceptive pill 3 month pack available to buy online from Dr Fox pharmacy.

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Buy Cerelle online

  1. Read medical information about the contraceptive pill
  2. Answer medical questions to check for eligibility
  3. Reviewed by doctors - medication posted from UK pharmacy (tracked 24hr service)

Prices

Prices of Cerelle from Dr Fox pharmacy
Contraceptive pillQuantityCost
Cerelle1 x 3 month pack£11.50

Price match guaranteePrice match guarantee
Prescription issued online - small prescription fee per order.

If you have your own private paper prescription please post to our pharmacy (details).

Prescription fees

Dr Fox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription.

Prescriptions are issued by our doctors online and sent electronically to our pharmacy.

If you have your own private paper prescription please post to our pharmacy (details).

Dr Fox prices are 25%–50% lower than other UK online clinics.

Order valuePrescription fee
up to £10£1.00
up to £20£2.00
up to £40£3.00
over £40£4.00

Delivery charges

UK delivery only: £2.90 per consultation via Royal Mail 24 Signed For (1-3 working days with tracking).

Parcel forwarding services are not permitted. Use only UK home or work delivery address.

Returns and refunds - unwanted items can be returned within 14 working days for a full refund.


About Cerelle

Cerelle is a progesterone-only contraceptive pill (POP or mini pill). It is a newer/modern type of POP, and the way it works to provide contraceptive is different to the older, traditional types of POPs such as Noriday and Norgeston.

Cerelle is the brand name of the product. Each pill contains the progesterone hormone desogestrel. Each pack of Cerelle consists of 28 active pills. One pill is taken every day. Each pack is started immediately when the previous pack finishes. There is no 7-day break.

Cerelle and Cerazette are medically the same - both contain desogestrel 75 microgram.

How to order?

Women who are eligible can order a 3-month supply of Cerelle if the following applies:

  • You have been taking Cerelle or Cerazette for the last year.
  • You have had no problems with your contraceptive pill in the last year.
  • You have had a face-to-face pill check at your GP surgery in the last year.

This service does not replace your regular face-to-face contraceptive pill check-up. We are required to inform your GP of any supplies and will require your GP surgery details.

How does Cerelle work as a contraceptive pill?

In days gone by, the progesterone-only pill (POP) was said to be less effective than the combined pill at preventing pregnancy. The older, traditional POPs, did not always work by preventing ovulation. For women who had medical reasons for not taking the combined pill, and were only able to take the POP, this was not very satisfactory.

But then a new generation of POPs appeared - notably Cerazette and Cerelle.

Cerazette and Cerelle are POPs which both work primarily to stop ovulation. These pills also affect cervical mucus, and cause changes to the lining of the womb, but their primary mode of action is to inhibit ovulation.

Cerazette and Cerelle are slightly easier to take than the traditional POPs. Because they inhibit ovulation, and are not relying on mucus changes, the rules about what time to take the pill are slightly more relaxed - you have 12 hours to remember to take your pill, as opposed to a 3 hour window with Noriday or Norgeston.

How effective is Cerelle?

The progesterone-only pill is 99% effective at preventing a pregnancy with 'perfect use'. With 'typical use' it is around 92% effective. Whichever pill you take - the combined pill or the POP - the pill only works as well as you take it.

Common side effects of Cerelle

Cerelle is generally well tolerated, and the likelihood of side effects is small. The most common side effects when taking Cerelle are listed as:

  • Menstrual cycles disrupted
  • Feeling sick or vomiting
  • Headache
  • Acne
  • Mood disturbance including depression
  • Reduced libido

Women's response to hormones is extremely variable. Most often, side effects are mild and settle over a few months.

Cerelle and weight gain

There is little good quality evidence about the POP and weight, but a 2016 Cochrane Data Review found no clear association between use of the POP, or other progesterone-only methods, and weight gain.

For the full list of potential side effects and what you need to know before taking Cerelle, please read the patient information leaflet supplied with the medicine.

What are the risks of Cerelle?

Serious side effects – adverse events - are very rare on the POP. However the contraceptive pill can only be prescribed for you if you are medically suitable. You will need regular pill checks with a doctor/nurse to continue to take it over the longer term.

Most of the (rare) serious, adverse events which occur in pill users are associated with use of the combined pill (which contains estrogen), and not with the POP (which is progesterone only).

Having reviewed the medical evidence, the Faculty of Sexual and Reproductive Healthcare (FSRH) have issued prescribing recommendations, which are summarised in the paragraph below. These are very different for the POP, than for the combined pill.

Use of a POP does not appear to produce an appreciable increase to the risk of:

  • Deep Vein Thrombosis (a blood clot).
  • Cardiovascular Disease – heart attacks and/or strokes.
  • Breast cancer.
  • Depression/mood changes.

Ovarian cysts – benign ovarian cysts are less common in users of Cerazette/Cerelle than in older POP pill type users.

There a very few medical conditions where the POP is contraindicated.

For example, the POP may be taken by women with:

  • Complicated diabetes.
  • Migraine with aura.
  • Heart disease.
  • A past history of a thrombosis (blood clot), or a stroke.
  • Aged over 35 and smoke.

All of the above are contraindications to taking the combined pill.

The POP should not be used by women in the following categories:

  • With a current or history of breast cancer within the last 5 years.
  • A malignant liver tumour.
  • Severe cirrhosis.
  • Acute porphyria.

When would taking Cerelle become an emergency?

Seek urgent medical help immediately if you develop any of the following:

  • Acute chest pain - it may hurt to breathe in, or cough.
  • Cough, breathlessness, coughing up blood.
  • Feeling dizzy, confusion, collapse.
  • A swelling of the lower leg.
  • Acute allergy (anaphylaxis) e.g. swelling of the lips, face, or tongue.
  • Heavy bleeding/severe pelvic pain. If you have heavy bleeding on Cerelle, consider the possibility of pregnancy. This could be due to miscarriage, or ectopic pregnancy.

What are the benefits of Cerelle?

  • Cerelle was first licensed in 2012, and is a newer POP, compared to the older progesterone-only pills Noriday and Norgeston. Cerelle and Cerazette are medically the same, and Cerazette has been licensed in the UK for more than 20 years - both do not appear to increase the risk of serious adverse events such as blood clots, heart attacks, or strokes.
  • Only 5% of British women use the POP, but many now take the newer POPs Cerelle and Cerazette, as these are easier to take.
  • Cerelle is a progestogen-only method, meaning there is no estrogen – so this is a pill which is safe for almost everybody to use. Long-term health risks are very small.
  • As a 'mini-pill' - the dose of hormone in the POP is small. Side effects in general, are likely to be less with a lower dose pill.
  • Taken perfectly, the POP Cerelle, offers excellent contraception, with a failure rate of less than 1 per 100 women per year.
  • Cerelle can be taken after giving birth and while breast feeding.
  • Cerelle is not associated with an increased risk of ectopic pregnancy.
  • Compared to a traditional POP, the likelihood of disrupted bleeding patterns with Cerelle is similar. (Around 20% of women in clinical studies dropped out because of this, in both groups.)
  • Cerelle like other POPs, is quickly reversible and fertility returns immediately on stopping.
  • Cerelle is taken every day, so there is no 7 day break, and this may be easier to take for some women.

What are the disadvantages of Cerelle?

  • Cerelle must be taken at the same time - or within 12 hours of that time - every day. There is no 7 day break. Perfect pill use can be difficult, especially with a busy lifestyle. Typical use failure rates are high, around 9%. Many women are now opting for Long Acting Reversible Contraception (LARC) such as IUD (coil), injection, or an implant.
  • The most common side effects are disturbances of bleeding. This usually settles in the first 3 months, but if it continues you must seek medical advice. Your doctor will advise what is needed - sometimes you may be advised to increase to 2 mini-pills per day, or to change to a different pill brand.
  • Some women get side effects from specific progesterones. Cerelle contains desogestrel, and if you and your doctor feel you have side effects from desogestrel, you may be advised to swap to a mini pill with a different progesterone.
  • There are small risks such as an increased risk of ovarian cysts.
  • Some drugs interfere with Cerelle (see below).

Which medicines interact with Cerelle?

The most common interactions are listed below:

  • Antibiotics - enzyme inducing antibiotics e.g. rifabutin and rifampicin, will interact, (but not other commonly used antibiotics.)
  • Antifungals - griseofulvin is also an enzyme inducer.
  • Antivirals - ritonavir, nelfinavir and nevirapine.
  • Anticonvulsants - barbiturates (including phenobarbitone) phenytoin, primidone, carbemazepine, oxcarbazepine and topiramate. Lamotrigine is not recommended.
  • Ulipristal acetate (UPA or EllaOne) - as a progesterone receptor blocker, if used with the POP, this could prevent the POP from working. If you take the emergency contraceptive pill while on the POP, you would generally not be offered UPA, but the alternative Levonelle (levonorgestrel 1.5mg). If you do take UPA because of missed POP pills, you should not restart POP until 5 days after taking it. This will be discussed with your doctor or local sexual health clinic.

What if I miss pills on Cerelle?

If you forget or miss a pill, you must follow the missed pill rules (FPA).

Patient Information Leaflet

Illustration of patient leaflet from medicine packet

The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine and must be read before taking the medicine. It is written for patients and gives information about taking or using a medicine.

Cerelle patient leaflet

Dr Tony Steele

Authored 02 July 2020 by Dr Tony Steele
MB ChB Sheffield University 1983. Former hospital doctor and GP.

Reviewed by Dr D. Lee, Dr A. Wood
Last reviewed 10 July 2020
Last updated 22 July 2020

References

Product reviews

Contraceptive pill rated 4.97/5 in 36 product reviews

See over 25,000 service reviews of Dr Fox

Marvelon

Great fast service

20/05/2020 21:03
Anonymous Verified

Lucette

for me no side effects at all, good price also. 5*

02/04/2020 12:08
E. Horvath Verified

Rigevidon

good product and fast delivery

18/09/2019 12:17
Anonymous Verified

Levest

Great would highly recommended

05/09/2019 17:25
F. Drake Verified

Cerazette

Unlike nothing else I’ve tried..

03/06/2019 11:43
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